在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae FACT complex subunit SPT16 (SPT16), partial

Recombinant Saccharomyces cerevisiae FACT complex subunit SPT16 (SPT16), partial

  • 中文名稱：
    釀酒酵母SPT16重組蛋白
  • 貨號：
    CSB-YP022955SVG
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母SPT16重組蛋白
  • 貨號：
    CSB-EP022955SVG
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母SPT16重組蛋白
  • 貨號：
    CSB-EP022955SVG-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母SPT16重組蛋白
  • 貨號：
    CSB-BP022955SVG
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母SPT16重組蛋白
  • 貨號：
    CSB-MP022955SVG
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SPT16
  • Uniprot No.：
  • 別名：
    SPT16; CDC68; SSF1; YGL207W; FACT complex subunit SPT16; Cell division control protein 68; Facilitates chromatin transcription complex subunit SPT16; Suppressor of Ty protein 16
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Transcription elongation is promoted by the repression of transcription initiation from cryptic sites. Also acts in establishing transcription initiation complexes and promotes SPT15/TBP-binding to a TATA box. Together with replication factor-A protein (RPA), FACT may play a role in nucleosome deposition during DNA replication.
  • 基因功能參考文獻：
    1. SPT16 interactions with nucleosome. PMID: 29271283
    2. Results show that Spt16 depletion results in global changes in nucleosome fuzziness and position shifts and that the majority of these changes are suppressed by inhibiting RNA polymerase II supporting a model in which Spt16 has a role in maintaining local nucleosome stability. PMID: 27141053
    3. These results suggest that the large scale overlap in Mot1 and Spt16 function arises from a combination of both their unique and shared functions in transcription complex assembly and chromatin structure regulation. PMID: 27226635
    4. Spt6 and FACT have both overlapping and distinct functional interactions with histones and nucleosomes and that binding to each of the components of a nucleosome is not sufficient to produce nucleosome reorganization PMID: 26416482
    5. results suggest that the discrimination of Spt16 to Htz1-bound genes is due to the priority of Chz1 over Spt16 in binding to the Htz1-bound genomic regions; Chz1-escorted Htz1 therefore impairs Spt16 binding at chromatin PMID: 24707933
    6. The Spt16 subunit of FACT is specifically required for H2B deposition onto rDNA genes. PMID: 23689130
    7. Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. PMID: 23417676
    8. Mutation that encodes the Spt16 subunit of FACT causes phenotypes associated with defects in transcription and replication. PMID: 21625001
    9. These findings identify Spt16 as an Rtt101 substrate, and suggest that Spt16 ubiquitylation is important for FACT to function during DNA replication. PMID: 20634314
    10. The FACT subunit Spt16 and Pkc1 signaling have an overlapping essential function, with an unexpected role for FACT in the maintenance of cell integrity. PMID: 19727824
    11. N-terminal region of Polalpha (Pol1p) that is evolutionarily conserved among different species interacts with Spt16p-Pob3p and Ctf4p in vivo PMID: 15485923
    12. The Spt16 N-terminal domain does become important under conditions of replication stress, where it mediates adaptation to stress conditions. PMID: 15520471
    13. Chd1 and SPT16 and POB3 act in opposition in regulating transcription. PMID: 17620414
    14. neither the Spt16 NTD nor a key residue in the putative Pob3-M-binding site was required for interactions with histone N termini or for yFACT-mediated nucleosome reorganization PMID: 18089575
    15. Spt16 restores normal nucleosome structure by redepositing the displaced H3-H4 histones, thereby preventing incorporation of new histones. PMID: 19683500

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
  • 蛋白家族：
    Peptidase M24 family, SPT16 subfamily
  • 數據庫鏈接：

    KEGG: sce:YGL207W

    STRING: 4932.YGL207W



主站蜘蛛池模板： 亚洲国产精品一区二区动图| 国产精品久久久久9999小说| 一本一道av无码中文字幕| 婷婷色中文字幕综合在线| 日本欧美一区二区免费视频| 一边啪啪一边呻吟av夜夜嗨| 情侣做性视频在线播放| 日韩一区二区三区无码影院 | 四虎永久在线精品884aa| 美女18禁一区二区三区视频| 强行糟蹋人妻hd中文字幕 | 护士奶头又大又软又好摸| 女厕厕露p撒尿八个少妇| 熟妇与小伙子matur老熟妇e | 边吃奶边添下面好爽| 国产国产成人久久精品| 亚洲精品v日韩精品| 成人aaa片一区国产精品| 欧美两根一起进3p做受视频| 欧美午夜片欧美片在线观看| 宝贝腿开大点我添添公视频免费| 九九九免费观看视频| 欧美性黑人极品hd另类| 性色av一二三天美传媒| 蜜臀av色欲a片无码一区二区| 亚洲男人av香蕉爽爽爽爽| 国产精品丝袜肉丝出水| 成人h无码动漫超w网站| 亚洲综合av一区二区三区| 国产98在线 | 日韩| 大香伊蕉在人线国产最新75 | 久久精品国产最新地址| 国产精品三级av及在线观看| 少妇无码av无码专区| 国产97在线 | 亚洲| 成 人 黄 色 大片| 久热这里只有精品12| 中国亚洲女人69内射少妇| 国产成人亚洲精品无码电影| 人妻系列无码专区无码中出| 久久不见久久见免费影院www|