Recombinant Saccharomyces cerevisiae Degradation in the endoplasmic reticulum protein 1 (DER1), partial

中文名稱：

釀酒酵母DER1重組蛋白
貨號：

CSB-YP336434SVG1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母DER1重組蛋白
貨號：

CSB-EP336434SVG1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母DER1重組蛋白
貨號：

CSB-EP336434SVG1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母DER1重組蛋白
貨號：

CSB-BP336434SVG1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母DER1重組蛋白
貨號：

CSB-MP336434SVG1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

DER1
Uniprot No.：

P38307
別名：

DER1; YBR201W; YBR1413; Degradation in the endoplasmic reticulum protein 1
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Specifically required for the ERAD-L pathway which mediates the degradation of proteins with misfolded lumenal domains within the endoplasmic reticulum (ER). Facilitates retrotranslocation of misfolded proteins from the ER lumen through the ER membrane in conjunction with HRD1. Both proteins have lateral gates facing each other and distort the membrane region between the lateral gates, making it much thinner than a normal phospholipid bilayer. Substrates insert into the membrane as a hairpin loop with one strand interacting with DER1 and the other with HRD1.
基因功能參考文獻(xiàn)：
1. Data indicate that N-terminal acetylation of Der1 regulates its degradation by the Hrd1 ligase. PMID: 23363603
2. Der1p degradation complex is enriched in a Cdc48p cofactor Ufd1p. PMID: 18407841
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

Derlin family
數(shù)據(jù)庫鏈接：

KEGG: sce:YBR201W

STRING: 4932.YBR201W