在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae DNA repair protein RAD5 (RAD5), partial

Recombinant Saccharomyces cerevisiae DNA repair protein RAD5 (RAD5), partial

  • 中文名稱：
    釀酒酵母RAD5重組蛋白
  • 貨號：
    CSB-YP335773SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母RAD5重組蛋白
  • 貨號：
    CSB-EP335773SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母RAD5重組蛋白
  • 貨號：
    CSB-EP335773SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母RAD5重組蛋白
  • 貨號：
    CSB-BP335773SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母RAD5重組蛋白
  • 貨號：
    CSB-MP335773SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RAD5
  • Uniprot No.：
  • 別名：
    RAD5; REV2; SNM2; YLR032W; DNA repair protein RAD5; EC 3.6.4.-; Radiation sensitivity protein 5; Revertibility protein 2
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with the DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs. Recruits the UBC13-MMS2 dimer to chromatin for DNA repair.
  • 基因功能參考文獻：
    1. By analyzing the formation of Rad5 foci after MMS treatment, we showed that some specific DNA structures rather than mono-ubiquitination of proliferating cell nuclear antigen are required for the recruitment of Rad5 to the damaged site PMID: 29396601
    2. Rad5 Ub-ligase and ATPase/helicase activities are required for the response to DNA damage. PMID: 25310987
    3. Data indicate that the DNA helicase Rad5 ubiquitin ligase activity does not require ATP. PMID: 25690888
    4. Findings suggest a structural role of the helicase domain of Rad5 and the helicase activity is dispensable for error-free lesion bypass. PMID: 24674630
    5. A survey of various yeast deletion mutants converged on the Rad5 pathway of DNA damage tolerance by template switching as the likely target pathway of NSC109268 in mediating cellular sensitization to cisplatin. PMID: 24130896
    6. Rad5 stably interacts with Rev1 via the N-terminal region of Rad5 and the C-terminal region of Rev1. PMID: 23142547
    7. we genetically characterized a conserved yeast ICL repair pathway composed of the yeast homologs (Mph1, Chl1, Mhf1, Mhf2) of four FA proteins (FANCM, FANCJ, MHF1, MHF2 PMID: 22696213
    8. The authors demonstrate that in the absence of PCNA SUMOylation, Mms2-Ubc13 and Rad5 may, independently of each other, function in the stimulation of translesion DNA synthesis. PMID: 21362066
    9. Results indicate that multiple activities of Rad5 function coordinately with homologous recombination factors to enable replication template switch events that join sister chromatids at stalled forks and bypass DNA damage. PMID: 20541998
    10. RAD5 contributes to DNA double-strand break repair via the Mre11/Rad50/Xrs2 protein complex. PMID: 16224103
    11. In contrast to the role of Rad5 in postreplicational repair, however, where its function is coupled with that of Mms2-Ubc13, Rad5 function in translesion synthesis would be largely independent of this ubiquitin-conjugating enzyme complex PMID: 16908531
    12. Data show that yeast Rad5 has a DNA helicase activity that is specialized for replication fork regression. PMID: 17936713
    13. Rad5 is required for DNA polymerase zeta-dependent translesion synthesis in Saccharomyces cerevisiae PMID: 18757916
    14. Rad5 acts both to align monoUb-PCNA with Ub-charged Ubc13 and to stimulate Ub transfer onto Lys(63) of a Ub acceptor. PMID: 19706603

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    SNF2/RAD54 helicase family
  • 數據庫鏈接：

    KEGG: sce:YLR032W

    STRING: 4932.YLR032W



主站蜘蛛池模板： 中文日韩亚洲欧美制服| 成人免费区一区二区三区| 久久电影网午夜鲁丝片免费| 欧美成人看片一区二区| 伊人成伊人成综合网222| 日韩卡二卡三卡四卡永久入口| 国产卡一卡二卡三精品| 乱人伦人妻精品一区二区| 3d动漫精品一区二区三区 | 久久精品日日躁夜夜躁| 暴力调教一区二区三区| 久久久精品中文字幕麻豆发布| 伊人大香人妻在线播放| 精品国产一区二区三区av色诱| 开心婷婷五月激情综合社区| 亚洲国产精品综合久久网络| 中出あ人妻熟女中文字幕| 欧美老妇疯狂xxxxbbbb| 亚洲欧洲中文日韩久久av乱码| 狠狠躁夜夜躁人人爽天天不卡| 日韩高清亚洲日韩精品一区| 亚洲国产精品无码av| 老熟女高潮喷水了| 无码免费毛片手机在线无卡顿 | 日韩中文字幕在线一区二区三区| 大香线蕉伊人超碰| 亚洲精品久久久无码大桥未久| 韩国v欧美v亚洲v日本v| 国产色在线 | 亚洲| 中文字幕丰满伦子无码| 97人摸人人澡人人人超碰| 国产精品99精品无码视亚| 国产美足白丝榨精在线观看sm| 无码综合天天久久综合网色吧影院 | 久久五十路丰满熟女中出 | 中文字幕乱码中文乱码51精品| 夜夜欢性恔免费视频| 无码中文字幕av免费放dvd| 无码成人一区二区三区| 国产白嫩漂亮美女在线观看| 成人无码a∨电影免费|