在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae DNA polymerase epsilon catalytic subunit A (POL2), partial

Recombinant Saccharomyces cerevisiae DNA polymerase epsilon catalytic subunit A (POL2), partial

  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-YP018309SVG
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-EP018309SVG
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-EP018309SVG-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-BP018309SVG
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-MP018309SVG
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    POL2
  • Uniprot No.：
  • 別名：
    POL2; DUN2; YNL262W; N0825DNA polymerase epsilon catalytic subunit A; EC 2.7.7.7; 3'-5' exodeoxyribonuclease; EC 3.1.11.-; DNA polymerase II subunit A
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalytic component of the DNA polymerase epsilon complex which participates in chromosomal DNA replication. Required during synthesis of the leading DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork. Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication.
  • 基因功能參考文獻：
    1. To dissect the Saccharomyces cerevisiae RNA polymerase II TL at individual-residue resolution, we quantitatively phenotyped nearly all TL single variants en masse.Our structural genetics approach incorporates structural and phenotypic data for high-resolution dissection of transcription mechanisms and their evolution, and is readily applicable to other essential yeast proteins. PMID: 27898685
    2. dNTP pool levels correlate with Pol epsilon mutator severity PMID: 25827226
    3. Authors report the presence of a [Fe-S] cluster directly within the active polymerase domain of Pol2 (residues 1-1187). PMID: 24144619
    4. Labeling of DNA polymerase epsilon catalytic subunit with the nick-containing DNA repair intermediate indicates that the DNA polymerase is involved in DNA repair in yeast PMID: 21601535
    5. show that subunits of DNA polymerase epsilon (Pol epsilon) are required but that Mrc1, a polymerase epsilon-associated checkpoint protein, is opposing senescence PMID: 21321081
    6. The active site location occupied by Met644 in Pol epsilon is a key determinant of DNA replication fidelity. PMID: 17452367
    7. RNAPII elongation is stimulated by H2B-K123 ubiquitination independent of H3-K4 methy PMID: 17543890
    8. findings reveal a pattern indicating that DNA polymerase epsilon participates in leading-strand DNA replication PMID: 17615360
    9. a mutation in the 3'-5' exonuclease domain of Pol2 dramatically reduces the frequency of end joins formed with initial 3' flaps. Thus, Pol2 performs a key 3' end-processing step in NHEJ. PMID: 18437220

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    DNA polymerase type-B family
  • 數據庫鏈接：

    KEGG: sce:YNL262W

    STRING: 4932.YNL262W



主站蜘蛛池模板： 精品国模一区二区三区| 人人澡人人曰人人摸看| 国产一本一道久久香蕉| 亚洲蜜桃v妇女| 7777精品伊人久久久大香线蕉| 国产av无码专区国产乱码| 国产一区二区三区在线蜜桃| 在线偷着国产精选视频| 男女啪啦啦超猛烈动态图| 四虎国产精品永久在线观看| 国产女同疯狂作爱系列| 国产亚洲精品ae86| 免费无码成人av片在线| 华人少妇被黑人粗大的猛烈进| 国产l精品国产亚洲区久久| 乱码视频午夜间在线观看| 欧美性猛少妇xxxxx免费| 精品无码久久久久久久久久| 亚洲人成精品久久久久| 亚洲日韩欧美一区久久久久我| 国产免费久久精品99reswag| 好吊色欧美一区二区三区四区| 久碰久摸久看视频在线观看| 欧美人与动牲交a欧美| 男人天堂2018亚洲男人天堂| 国产成人无码激情视频| 6699嫩草久久久精品影院| 久久午夜夜伦鲁鲁片无码免费| 免费现黄频在线观看国产| 丰满少妇在线观看网站| 色多多性虎精品无码av| 国产在线观看精品一区二区三区 | 成人区精品一区二区不卡| 国产精品久久国产精麻豆99网站| 国产三级在线观看完整版| 中文在线а√天堂官网| 日本一区二区三区不卡免费| 精品国产三级a∨在线欧美| 中文字幕乱码免费看电影| 国产成人精品免费视频大全五级| 国产美女精品视频线免费播放软件|