在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae DNA polymerase epsilon catalytic subunit A (POL2), partial

Recombinant Saccharomyces cerevisiae DNA polymerase epsilon catalytic subunit A (POL2), partial

  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-YP018309SVG
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-EP018309SVG
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-EP018309SVG-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-BP018309SVG
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母POL2重組蛋白
  • 貨號：
    CSB-MP018309SVG
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    POL2
  • Uniprot No.：
  • 別名：
    POL2; DUN2; YNL262W; N0825DNA polymerase epsilon catalytic subunit A; EC 2.7.7.7; 3'-5' exodeoxyribonuclease; EC 3.1.11.-; DNA polymerase II subunit A
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalytic component of the DNA polymerase epsilon complex which participates in chromosomal DNA replication. Required during synthesis of the leading DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork. Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication.
  • 基因功能參考文獻：
    1. To dissect the Saccharomyces cerevisiae RNA polymerase II TL at individual-residue resolution, we quantitatively phenotyped nearly all TL single variants en masse.Our structural genetics approach incorporates structural and phenotypic data for high-resolution dissection of transcription mechanisms and their evolution, and is readily applicable to other essential yeast proteins. PMID: 27898685
    2. dNTP pool levels correlate with Pol epsilon mutator severity PMID: 25827226
    3. Authors report the presence of a [Fe-S] cluster directly within the active polymerase domain of Pol2 (residues 1-1187). PMID: 24144619
    4. Labeling of DNA polymerase epsilon catalytic subunit with the nick-containing DNA repair intermediate indicates that the DNA polymerase is involved in DNA repair in yeast PMID: 21601535
    5. show that subunits of DNA polymerase epsilon (Pol epsilon) are required but that Mrc1, a polymerase epsilon-associated checkpoint protein, is opposing senescence PMID: 21321081
    6. The active site location occupied by Met644 in Pol epsilon is a key determinant of DNA replication fidelity. PMID: 17452367
    7. RNAPII elongation is stimulated by H2B-K123 ubiquitination independent of H3-K4 methy PMID: 17543890
    8. findings reveal a pattern indicating that DNA polymerase epsilon participates in leading-strand DNA replication PMID: 17615360
    9. a mutation in the 3'-5' exonuclease domain of Pol2 dramatically reduces the frequency of end joins formed with initial 3' flaps. Thus, Pol2 performs a key 3' end-processing step in NHEJ. PMID: 18437220

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    DNA polymerase type-B family
  • 數據庫鏈接：

    KEGG: sce:YNL262W

    STRING: 4932.YNL262W



主站蜘蛛池模板： 成人一在线视频日韩国产| 欧美老熟妇乱子伦视频| 亚洲伊人久久综合影院| 四虎影视国产精品久久| 午夜成人无码片在线观看影院| 久久久肥妇熟女ⅹxxx毛片| 熟妇人妻无码中文字幕| 亚洲国产成人精品无码区99| 怡红院a∨人人爰人人爽| 伊人激情av一区二区三区| 久久人人97超碰国产亚洲人 | 国产成人精品免费视频大全软件| 国产内射爽爽大片| 精品人伦一区二区三区蜜桃免费 | 亚洲免费观看在线视频| 图片区小说区激情区偷拍区| 亚洲中文字幕乱码一区| 在线精品无码字幕无码av| 国产日韩一区二区三免费高清| 国产99久久九九精品无码| 在线观看国产午夜福利片| 一本色道久久88亚洲精品综合| 性欧美大胆免费播放| 欧美猛少妇色xxxxx猛叫| 无码国内精品久久人妻蜜桃| 浪货趴办公桌～h揉秘书电影| 黑人巨大精品欧美| 激情无码人妻又粗又大| 人妻体内射精一区二区| 日产日韩亚洲欧美综合下载| 无码av无码天堂资源网影音先锋| 欧美成人一区二区三区片免费| 中文字幕无码不卡免费视频| 国产精品高潮呻吟av久久| 亚洲性视频免费视频网站| 高清无码爆乳潮喷在线观看 | 两个黑人大战嫩白金发美女| 欧美粗大猛烈老熟妇| 性xxxxx欧美极品少妇| 日韩aⅴ人妻无码一区二区| 国产精品无码一区二区桃花视频|