Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit (CKS1)

中文名稱：

Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit(CKS1)
貨號：

CSB-YP324942SVG
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit(CKS1)
貨號：

CSB-EP324942SVG
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit(CKS1)
貨號：

CSB-EP324942SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit(CKS1)
貨號：

CSB-BP324942SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cyclin-dependent kinases regulatory subunit(CKS1)
貨號：

CSB-MP324942SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CKS1
Uniprot No.：

P20486
別名：

CKS1; YBR135W; YBR1011Cyclin-dependent kinases regulatory subunit; Cell division control protein CKS1
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-150
氨基酸序列

MYHHYHAFQG RKLTDQERAR VLEFQDSIHY SPRYSDDNYE YRHVMLPKAM LKVIPSDYFN SEVGTLRILT EDEWRGLGIT QSLGWEHYEC HAPEPHILLF KRPLNYEAEL RAATAAAQQQ QQQQQQQQQQ QQQHQTQSIS NDMQVPPQIS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to the catalytic subunit of the cyclin dependent kinase (CDC28) and is essential for its biological function.
基因功能參考文獻：
1. Mutation of the polo-like kinase Cdc5, which functions in both the mitotic entry and mitotic exit pathways, is lethal in combination with overexpressed CKS1 PMID: 27558135
2. Cks1 mediates recruitment of the 19S proteasome to the Paf1 complex, thereby promoting transcriptional elongation. PMID: 23825181
3. conservation of Cks hinge-region prolines reflects their functions in forming a Cdk binding interface and that ability of these prolines to control partitioning between monomer and dimer is a consequence of the beta-turn networks within the hinge. PMID: 21704044
4. These data suggest a model where binding of a complex consisting of Cks1, Cdk1, and the 19S proteasome to histone H4 leads to removal of nucleosomes via a nonproteolytic activity of the proteasome. PMID: 20855529
5. function in transcription for the cell cycle regulatory cyclin-dependent kinase Cdc28 (Cdk1) and its interacting protein, Cks1 PMID: 15629725
6. the first report of a direct physical interaction between ubiquitin and Cks1p, inferring a role for ubiquitin binding in the transcriptional function of Cks1p PMID: 17198374
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蛋白家族：

CKS family
數據庫鏈接：

KEGG: sce:YBR135W

STRING: 4932.YBR135W