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  4. Recombinant Saccharomyces cerevisiae Autophagy-related protein 19 (ATG19)

Recombinant Saccharomyces cerevisiae Autophagy-related protein 19 (ATG19)

  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 19(ATG19)
  • 貨號：
    CSB-YP327404SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 19(ATG19)
  • 貨號：
    CSB-EP327404SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 19(ATG19)
  • 貨號：
    CSB-EP327404SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 19(ATG19)
  • 貨號：
    CSB-BP327404SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 19(ATG19)
  • 貨號：
    CSB-MP327404SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ATG19
  • Uniprot No.：
  • 別名：
    ATG19; CVT19; YOL082W; O0980; YOL01Autophagy-related protein 19; Cytoplasm-to-vacuole targeting protein 19
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-415
  • 氨基酸序列
    MNNSKTNQQM NTSMGYPLTV YDECNKFQLI VPTLDANIML WCIGQLSLLN DSNGCKHLFW QPNDKSNVRI LLNNYDYGHL FKYLQCQRKC SVYIGEGTLK KYNLTISTSF DNFLDLTPSE EKESLCREDA HEDPVSPKAG SEEEISPNST SNVVVSRECL DNFMKQLLKL EESLNKLELE QKVTNKEPNH RISGTIDIPE DRSELVNFFT ELKTVKQLED VFQRYHDYER LSQECDSKTE IASDHSKKET KIEVEPPNER SLQITMNQRD NSLYFQLFNN TNSVLAGNCK LKFTDAGDKP TTQIIDMGPH EIGIKEYKEY RYFPYALDLE AGSTIEIENQ YGEVIFLGKY GSSPMINLRP PSRLSAESLQ ASQEPFYSFQ IDTLPELDDS SIISTSISLS YDGDDNEKAL TWEEL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as APE4, LAP3, LAP4 and AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole. Involved in the organization of the preautophagosomal structure (PAS). ATG19 association with cargo protein is required to localize ATG11 to the PAS. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates, and is essential for the survival of cells subjected to severe ER stress. Plays also a role in regulation of filamentous growth.
  • 基因功能參考文獻：
    1. The essential kinase Hrr25 activates the cargo receptor Atg19 by phosphorylation. PMID: 24968893
    2. both ubiquitination and deubiquitination of Atg19p are required for its full function PMID: 16186126
    3. Atg19 mediates a dual interaction prApe1-sorting mechanism through independent, instead of sequential, interactions with Atg11 and Atg8. PMID: 17192412
    4. ATG19 takes part in the cytoplasm to vacuole targeting pathway for an efficient degradation of misfolded Pma1 PMID: 17238920
  • 亞細胞定位：
    Preautophagosomal structure membrane; Peripheral membrane protein. Note=Also found in other perivacuolar punctate structures.
  • 數據庫鏈接：

    KEGG: sce:YOL082W

    STRING: 4932.YOL082W



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