在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2 (Cacnb2)

Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2 (Cacnb2)

  • 中文名稱：
    Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2(Cacnb2)
  • 貨號：
    CSB-YP837733RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2(Cacnb2)
  • 貨號：
    CSB-EP837733RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2(Cacnb2)
  • 貨號：
    CSB-EP837733RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2(Cacnb2)
  • 貨號：
    CSB-BP837733RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Voltage-dependent L-type calcium channel subunit beta-2(Cacnb2)
  • 貨號：
    CSB-MP837733RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cacnb2; Cacnlb2; Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Calcium channel voltage-dependent subunit beta 2
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-655
  • 氨基酸序列
    MVQSDTSKSP PIAAVAQESQ MELLESAAPA GALGAQSYGK GARRKNRFKG SDDSTSSDTT SNSFVRQGSA DSYTSRPSDS DVSLEEDREA VRREAERQAQ AQLEKAKTKP VAFAVRTNVR YSAAQEDDVP VPGMAISFEA KDFLHVKEKF NNDWWIGRLV KEGCEIGFIP SPVKLENMRL QHEQRAKQGK FYSSKSGGNS SSSLGDIVPS SRKSTPPSSA IDIDATGLDA EENDIPANHR SPKPSANSVT SPHSKEKRMP FFKKTEHTPP YDVVPSMRPV VLVGPSLKGY EVTDMMQKAL FDFLKHRFEG RISITRVTAD ISLAKRSVLN NPSKHAIIER SNTRSSLAEV QSEIERIFEL ARTLQLVVLD ADTINHPAQL SKTSLAPIIV YVKISSPKVL QRLIKSRGKS QAKHLNVQMV AADKLAQCPP QESFDVILDE NQLEDACEHL ADYLEAYWKA THPPSSNLPN PLLSRTLATS TLPLSPTLAS NSQGSQGDQR TDRSAPRSAS QAEEEPCLEP VKKSQHRSSS ATHQNHRSGT GRGLSRQETF DSETQESRDS AYVEPKEDYS HEHVDRYVPH REHNHREESH SSNGHRHREP RHRTRDMGRD QDHNECSKQR SRHKSKDRYC DKEGEVISKR RSEAGEWNRD VYIRQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 基因功能參考文獻：
    1. these findings provide evidence for a new role of Homer1 supporting the regulation of Cav1.2 channels by STIM1. PMID: 25712868
    2. Cacnb2 is selectively targeted to the axon terminals of supraoptic neurons. PMID: 24755552
    3. a model in which CaVbeta promotes anterograde trafficking of the L-type channels by anchoring them to actin filaments in their itinerary to the plasma membrane. PMID: 25533460
    4. analysis of how voltage-gated calcium channel beta2e-subunit N-terminal domain is tethered to the plasma membrane via electrostatic and hydrophobic interactions PMID: 24519939
    5. Data show that ablation of L-type calcium channels partially blocks Akt inhibition-induced reduction in glucose-stimulated insulin secretion but completely prevents that in potassium depolarization-evoked insulin release from INS-1 cells. PMID: 21792084
    6. Cardiac L-type Ca channel beta2 subunit protein expression may be downregulated by miRs in response to long-term activation of beta-adrenergic signaling, possibly as an adaptive response in cardiac hypertrophy and sustained beta-adrenergic states. PMID: 21753737
    7. Beta subunits play a role in PKA modulation of Ca(V)1.2 channels and uncover a new design principle of this phenomenon in the heart, vis a vis a limited functional reserve. PMID: 18356540
    8. This study provides the first evidence to demonstrate that LTCC beta2 subunit is coupled with the movement of signals in the mechanism of activation of NKA-mediated crosstalk with LTCC. PMID: 20937253
    9. CaMKII specifically binds to CaV1.2 L-type calcium channels by the beta(1b) or beta(2a) subunits. PMID: 19840220
    10. a novel function for the beta-subunit through its Src homology 3 domain and establish a link between voltage-gated calcium channel activity and the cell endocytic machinery PMID: 17110381

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Calcium channel beta subunit family
  • 組織特異性：
    Highly expressed in heart and brain, and at lower levels in lung.
  • 數據庫鏈接：


主站蜘蛛池模板： av天堂午夜精品蜜臀av| 高清无码一区二区在线观看吞精 | 欧美日本国产va高清cabal| 国产亚洲情侣一区二区无| 无码中文人妻在线一区| 国产一区精选播放022| 人妻精品久久久久中文字幕69| 高清偷自拍第1页| 最新成年女人毛片免费基地| 日本亚洲vr欧美不卡高清专区| 亚洲成年轻人电影网站www| 国产精品视频一区二区三区不卡 | 欧美巨大xxxx做受高清| 精品免费国产一区二区| 成人免费无码大片a毛片抽搐| 无码丰满熟妇juliaann与黑人| 隔壁老王国产在线精品| 亚洲国产欧美不卡在线观看| 果冻传媒亚洲区二期| 无码人妻一区二区三区免费看成人 | 无码人妻精品一区二区蜜桃百度 | 欧美性生交xxxxx久久久| 欧美人成视频在线视频| 亚洲欧洲日韩综合久久| 国产成人精品999在线观看| 久久人人爽人人爽人人av东京热| 午夜成人爽爽爽视频在线观看| 国产精品成人观看视频国产奇米| 伊人久久大香线蕉亚洲五月天| 国产无套内射普通话对白| 国产福利男女xx00视频| 国产亚洲视频在线观看网址 | 狂野欧美性猛交xxxx| 久久久国产精华液| 日韩av无码一区二区三区无码 | 国产成 人 综合 亚洲| 曰本av中文字幕一区二区| 成人性生交片无码免费看| 亚洲欧洲∨国产一区二区三区| 国偷自产一区二区三区在线视频| 五十路熟女一区二区三区|