在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Tyrosine-protein phosphatase non-receptor type 6 (Ptpn6)

  • 中文名稱:
    大鼠Ptpn6重組蛋白
  • 貨號(hào):
    CSB-YP019043RA
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Ptpn6重組蛋白
  • 貨號(hào):
    CSB-EP019043RA
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Ptpn6重組蛋白
  • 貨號(hào):
    CSB-EP019043RA-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Ptpn6重組蛋白
  • 貨號(hào):
    CSB-BP019043RA
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Ptpn6重組蛋白
  • 貨號(hào):
    CSB-MP019043RA
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ptpn6; Ptph6; Tyrosine-protein phosphatase non-receptor type 6; EC 3.1.3.48; Protein-tyrosine phosphatase SHP-1
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-613
  • 氨基酸序列
    MLSRGWFHRD LSGPDAETLL KGRGVPGSFL ARPSRKNQGD FSLSVRVDDQ VTHIRIQNSG DFYDLYGGEK FATSTELVEY YTQQQGILQD RDGTIIHLKY PLNCSDPTSE RWYHGHMSGG QAESLLQAKG EPWTFLVRES LSQPGDFVLS VLNDQPKAAP GSPLRVTHIK VMCEGGRYTV GGSETFDSLT DLVEHFKKTG IEEASGAFVY LRQPYYATRV NAADIENRVL ELNKKQESED TAKAGFWEEF ESLQKQEAKN LHQRLEGQRP ENKSKNRYKN ILPFDHSRVI LQGRDSNIPG SDYINANYVK NQLLGPDENS KTYIASQGCL DATVNDFWQM AWQENTRVIV MTTREVEKGR NKCVPYWPEV GTQRVYGLYS VTNCKEHDTA EYKLRTLQIS PLDNGDLVRE IWHYQYLSWP DHGVPSEPGG VLSFLDQINQ RQESLPHAGP IIVHCSAGIG RTGTIIVIDM LMESVSTKGL DCDIDIQKTI QMVRAQRSGM VQTEAQYKFI YVAIAQFIET TKKKLEIIQS QRGQESEYGN ITYPPALRSA HAKASRTSSK HKEEVYENVH SKNKKEEKVK KQRSADKEKN KGSLKRNISL TPCRGLRWAD RDL
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
  • 基因功能參考文獻(xiàn):
    1. Shp-1 increased in DRGs of rats with CFA-induced inflammatory pain, which was involved in protecting against excessive thermal hyperalgesia. PMID: 25790452
    2. Andrographolide activates the PP2A-p38MAPK-p53-Bax cascade. PMID: 25007834
    3. SHP-1 as an off-switch of PDGFR signaling appears to emerge as a valuable molecular target to trigger as to prevent hepatic stellate cells (HSC) proliferation and the fibrogenic effects of HSC activation. PMID: 24140598
    4. Postnatal day-15 hindbrain contains a complex of proteins recruited by angiotensin (Ang)-II SHP-1 protein tyrosine activation, which participates in an active signal transduction mechanism. PMID: 22120166
    5. The activity of SHP-1 was decreased after high partial pressure of oxygen treatment no matter what the duration was, while the activity of CD45 was decreased only after high partial pressure of oxygen that led to inhibition of lymphocyte function. PMID: 21166153
    6. Adaptor protein 3BP2 directly interacts with Tyr564-phosphorylated form of SHP-1 and positively regulates the function of SHP-1 in FcepsilonRI-mediated signaling in mast cells. PMID: 22077594
    7. Nicotine-induced tyrosine phosphorylation of JAK2 and neuroprotection against Abeta (1-42) in PC12 cells are blocked by Ang II via AT2 receptor-induced activation of SHP-1 PMID: 14657181
    8. Src homology protein tyrosine phosphatase-1 might play a critical role in the transcriptional regulation of MCP-1 expression PMID: 14684844
    9. SHP-1 may play a role in limiting CNS inflammation following injury such as deafferenting the auditory brainstem. PMID: 15341919
    10. SHP-1 has a role in myocardial infarction in rats PMID: 16223786
    11. SHP-1 phosphatase activation, by Angiotensin II (Ang II) AT(2) receptors Involvement of c-Src tyrosine kinase PMID: 18680145

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Non-receptor class 2 subfamily
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 国产成人精品999在线观看| 国产精品夜间视频香蕉| 亚洲色成人网站www永久四虎| 亚洲色播爱爱爱爱爱爱爱| 亚洲综合av色婷婷| 中国国产免费毛卡片| 欧美国产激情一区二区在线| 国产99视频精品免费视频6| 女人国产香蕉久久精品| 国产一区二区三精品久久久无广告 | 曰韩内射六十七十老熟女影视| 亚洲欧美日韩国产成人精品影院 | 国产乡下妇女做爰| 疯狂做受xxxx高潮不断| 污污又黄又爽免费的网站| 玩弄丰满熟妇xxxxx性60 | 日本少妇高潮喷水免费可以看| 亚洲欧美偷拍另类a∨| 亚洲精品无码不卡在线播放| 宅女午夜福利免费视频| 波多野结av衣东京热无码专区| 国产午夜福利片| 少妇白浆呻吟爽| 成人免费无码不卡毛片| 亚洲精品久久久久久中文| 国产成人精品日本亚洲第一区| 日日鲁鲁鲁夜夜爽爽狠狠 | 亚洲国产天堂久久综合| 成人午夜高潮刺激免费视频| 亚洲伊人成无码综合影院| 久久国产色av免费观看| 日产一区日产2区| 成人试看30分钟免费视频| 亚洲成亚洲成网| 国产高清自产拍av在线| 爽爽精品dvd蜜桃成熟时电影院| 国产熟妇午夜精品aaa| 超caopor在线公开视频| √天堂资源在线中文8在线最新版| 国产一区二区三区美女| 中文在线最新版天堂|