在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Type-1 angiotensin II receptor-associated protein (Agtrap), partial

  • 中文名稱:
    Recombinant Rat Type-1 angiotensin II receptor-associated protein(Agtrap),partial
  • 貨號:
    CSB-YP727055RA1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rat Type-1 angiotensin II receptor-associated protein(Agtrap),partial
  • 貨號:
    CSB-EP727055RA1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Rat Type-1 angiotensin II receptor-associated protein(Agtrap),partial
  • 貨號:
    CSB-EP727055RA1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rat Type-1 angiotensin II receptor-associated protein(Agtrap),partial
  • 貨號:
    CSB-BP727055RA1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rat Type-1 angiotensin II receptor-associated protein(Agtrap),partial
  • 貨號:
    CSB-MP727055RA1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Agtrap
  • Uniprot No.:
  • 別名:
    Agtrap; Atrap; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway. Attenuates type-1 angiotensin II receptor growth promoting effect and angiotensin II-induced phosphorylation of protein kinase AKT and of STAT3.
  • 基因功能參考文獻:
    1. A single dose of angiotensin(17) at the same concentration as angiotensin II induced Agtrap gene expression. PMID: 26018598
    2. The expression of both angiotensin AGTRa and AGTR2 receptors was increased in the myocardium of overfed rats, and ischemia-reperfusion increased the expression of both receptors in control rats but reduced it in overfed rats. PMID: 23383303
    3. AT(1)-AB induces Ang II sensitivity. Our mechanistic study supports the existence of an "autoimmune-activating receptor" that could contribute to Ang II sensitivity and possible to preeclampsia. PMID: 21576625
    4. results suggest that the local renin-angiotensin system is activated in diabetic skin and Angiotensin II receptors type 1 and 2 are likely to mediate the pathological changes of diabetic skin PMID: 21484513
    5. These results show that adipocyte-derived angiotensin II is critically involved in perivascular adipose tissue-mediated potentiation of vasoconstriction in mesenteric arteries. PMID: 20156432
    6. Long-term selective Ang II blockade ameliorates insulin resistance in adipose tissue from a model of metabolic syndrome. PMID: 19901849
    7. The growth inhibitory effects of ATRAP might be due to interfering with angiotensin 1 receptor activation in vascular smooth muscle cell growth. PMID: 17441313
    8. ATRAP promotes internalization of AT1R and attenuates the angiotensin II-mediated c-fos-transforming growth factor-beta pathway and proliferative response in vascular smooth muscle cells, suggesting a strategy to inhibit vascular fibrosis and remodeling PMID: 17875818
    9. Angiotensin II distinctly upregulated TLR4 expression in the cells. PMID: 19471094

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲欧美色αv在线影视| av在线观看地址| 亚洲日韩av一区二区三区中文| 中文天堂最新版在线www| 最新的国产成人精品2021| 中老年熟妇激情啪啪大屁股| 护士人妻hd中文字幕| 国产精品美女一区二区视频| 国产桃色无码视频在线观看| 天堂va视频一区二区| 国产精品一区二区av在线观看 | 日韩欧美亚洲综合久久影院| 成人做爰69片免费看网站| 中文字幕一区二区三区精华液| 影音先锋无码a∨男人资源站| 好男人在线社区www在线影院| 亚洲va国产va天堂va久久| 国产成+人+综合+亚洲欧美丁香花| av天堂中av世界中文在线播放| 国产第一页浮力影院草草| 亚洲精品国产suv| 7777精品久久久大香线蕉| 亚洲一线产区二线产区分布| 亚洲色无码播放| 真人作爱免费视频| 中文在线а天堂| 97久久超碰成人精品网站| 性欧美丰满熟妇xxxx性仙踪林| 欧美亚洲国产成人一区二区三区| a狠狠久久蜜臀婷色中文网| 玩两个丰满老熟女久久网| 丰满肥臀大屁股熟妇激情视频| 精品无码久久久久久久久| 国产99青草视频在线播放视| 麻豆av久久av盛宴av| 牛牛在线视频| 2021久久精品国产99国产精品| 在线a毛片免费视频观看| 人人妻人人澡人人爽人人精品电影| 少妇无套内谢久久久久| 国语高潮无遮挡无码免费看|