在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Troponin I, slow skeletal muscle (Tnni1)

Recombinant Rat Troponin I, slow skeletal muscle (Tnni1)

  • 中文名稱：
    大鼠Tnni1重組蛋白
  • 貨號：
    CSB-YP319539RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Tnni1重組蛋白
  • 貨號：
    CSB-EP319539RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Tnni1重組蛋白
  • 貨號：
    CSB-EP319539RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Tnni1重組蛋白
  • 貨號：
    CSB-BP319539RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Tnni1重組蛋白
  • 貨號：
    CSB-MP319539RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tnni1
  • Uniprot No.：
  • 別名：
    Tnni1; Troponin I; slow skeletal muscle; Troponin I; slow-twitch isoform
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-187
  • 氨基酸序列
    MPEVERKSKI TASRKLMLKS LMLAKAKECW EQEHEEREAE KVRYLSERIP TLQTRGLSLS ALQDLCRELH AKVEVVDEER YDIEAKCLHN TREIKDLKLK VLDLRGKFKR PPLRRVRVSA DAMLRALLGS KHKVSMDLRA NLKSVKKEDT EKERPVEVGD WRKNVEAMSG MEGRKKMFDA AKSPTLQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • 基因功能參考文獻：
    1. these results suggest that cTnI(R146G) and cTnI(R21C) blunt PKA modulation of activation and relaxation kinetics by prohibiting cardiac-specific N-terminal interaction with the cTnI inhibitory peptide. PMID: 26391394
    2. troponin I phosphorylation has a role in protein kinase C-mediated enhanced contractile performance of myocytes PMID: 12815045
    3. A novel role is described for cardiac TnI PKA phosphorylation in the rate-dependent enhancement of systolic & diastolic function in vivo & afterload sensitivity of relaxation. This has implications for cardiac failure. PMID: 14726477
    4. MuRF1 functions as a ubiquitin ligase to catalyze ubiquitylation of troponin I through a RING finger-dependent mechanism PMID: 15601779
    5. TnI-isoform and titin-isoform switching and corresponding functional changes during heart development are not initiated by birth but are genetically programmed PMID: 16679402
    6. The goal here was to identify domain clusters and residues that confer troponin I isoform-specific myofilament Ca2+ and pH sensitivities of contraction. PMID: 17602701
    7. This study highlights cellular contractile defects by cardiomyopathy mutant cTnIs that are allele and species dependent. PMID: 18423659
    8. Study identifies tyrosine phosphorylation as a novel protein kinase Cdelta (PKCdelta) activation mechanism that modifies PKCdelta-dependent phosphorylation of cardiac troponin I. PMID: 18550549
    9. The negative inotropic effect of HIV gp120 is mediated by a novel signaling pathway that begins with binding to a cardiac myocyte CXCR4 receptor, followed by phosphorylation of both p38 MAP kinase and Troponin I. PMID: 18850076
    10. observed higher relative level of natural antisense RNA in neonatal cardiac fibroblasts compared to neonatal cardiomyocytes, pointing to a cell type-specific expression of sense and antisense RNA PMID: 19184367
    11. These findings suggest that altered TnI function, due to changes in the distribution of phosphorylated sites, is an early contributor to reduced contractility of the heart. PMID: 19507043

    顯示更多

    收起更多

  • 蛋白家族：
    Troponin I family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产精品白丝喷水在线观看| 亚洲最大激情中文字幕| 国产成人精品a∨一区二区| 久久一日本综合色鬼综合色| 国产精品久久久久久亚洲色| 亚洲中文字幕无码中字| 2018国产精华国产精品| 久久国产美女精品久久| 男女下面一进一出好爽视频| 狠狠综合久久久久尤物| 无码人妻一区二区三区线| 久久久久久毛片免费播放| 又黄又硬又湿又刺激视频免费| 人间精品视频在线播放| 天天综合网天天综合色| 中文天堂在线www| 亚洲女教师丝祙在线播放| 六十熟妇乱子伦视频| 亚洲人毛茸茸bbxx| 狠狠综合久久av一区二区| 欧美人牲口杂交在线播放免费 | 久久国产午夜精品理论片34页| 伊人99综合精品视频| 明星性猛交ⅹxxx乱大交| 高大丰满熟妇丰满的大白屁股 | 久久精品无码专区免费青青| 中文字幕人妻熟在线影院| 国产精品h片在线播放| 国产人成视频在线视频| 超碰国产天天做天天爽| 嫩草研究院久久久精品| 人与禽交videos欧美| 国内大量揄拍人妻精品視頻| 精品久久国产综合婷婷五月| 欧洲美熟女乱又伦av| 精品免费国产一区二区三区四区| 精品人妻一区二区三区四区| 免费人成网视频在线观看| 亚洲人精品亚洲人成在线| 少妇无码吹潮| 粉嫩被粗大进进出出视频|