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  4. Recombinant Rat Tricarboxylate transport protein, mitochondrial (Slc25a1), partial

Recombinant Rat Tricarboxylate transport protein, mitochondrial (Slc25a1), partial

  • 中文名稱(chēng)：
    大鼠Slc25a1重組蛋白
  • 貨號(hào)：
    CSB-YP021475RA1
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    大鼠Slc25a1重組蛋白
  • 貨號(hào)：
    CSB-EP021475RA1
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    大鼠Slc25a1重組蛋白
  • 貨號(hào)：
    CSB-EP021475RA1-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    大鼠Slc25a1重組蛋白
  • 貨號(hào)：
    CSB-BP021475RA1
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    大鼠Slc25a1重組蛋白
  • 貨號(hào)：
    CSB-MP021475RA1
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Slc25a1; Slc20a3; Tricarboxylate transport protein, mitochondrial; Citrate transport protein; CTP; Solute carrier family 25 member 1; Tricarboxylate carrier protein
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation.
  • 基因功能參考文獻(xiàn)：
    1. Results suggest that in starved rats the regulation of hepatic citrate carrier expression occurs at posttranscriptional level. PMID: 12445817
    2. Data show that the citrate carrier (CIC) presequence was found to be dispensable both for targeting to mitochondria and insertion into the inner membrane. PMID: 12488104
    3. administration of n-6 PUFAs to rats leads to changes not only in the transcriptional rate of the tricarboxylate (citrate) carrier gene but also in the processing of the nuclear precursor for TCC RNA. PMID: 15060089
    4. Different dietary fatty acids have dissimilar effects on activity and gene expression of Ctp. PMID: 15589833
    5. Data show that under conditions of increased ionic strength, the citrate carrier precursor protein presequence binds to Tom20 and accumulates at the mitochondrial surface. PMID: 16129883
    6. that export of citrate and/or isocitrate from the mitochondria to the cytosol through Slc25a1 is an important step in control of glucose-stimulated insulin secretion PMID: 17001083

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  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 數(shù)據(jù)庫(kù)鏈接：


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