在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Transcription intermediary factor 1-beta (Trim28), partial

Recombinant Rat Transcription intermediary factor 1-beta (Trim28), partial

  • 中文名稱：
    大鼠Trim28重組蛋白
  • 貨號：
    CSB-YP024465RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Trim28重組蛋白
  • 貨號：
    CSB-EP024465RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Trim28重組蛋白
  • 貨號：
    CSB-EP024465RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Trim28重組蛋白
  • 貨號：
    CSB-BP024465RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Trim28重組蛋白
  • 貨號：
    CSB-MP024465RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Trim28; Kap1; Tif1b; Transcription intermediary factor 1-beta; TIF1-beta; E3 SUMO-protein ligase TRIM28; EC 2.3.2.27; KRAB-associated protein 1; Nuclear corepressor KAP-1; RING-type E3 ubiquitin transferase TIF1-beta; Tripartite motif-containing protein 28
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors. In association with isoform 2 of ZFP90, is required for the transcriptional repressor activity of FOXP3 and the suppressive function of regulatory T-cells (Treg). Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells. Required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs). In ESCs, in collaboration with SETDB1, is also required for H3K9me3 and silencing of endogenous and introduced retroviruses in a DNA-methylation independent-pathway. Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc finger genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions. Acts as a corepressor for ZFP568.
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲午夜成人av电影| 国产制服丝袜亚洲高清| 国产免费爽爽视频在线观看| 中日韩产精品1卡二卡三卡| 女人扒开屁股桶爽30分钟| 欧美人与动牲交zooz乌克兰| 久草热8精品视频在线观看 | 亚洲a片国产av一区无码| 麻豆ā片免费观看在线看| 久久婷婷五月综合国产尤物app| 国产精品妇女一二三区| 国产69精品久久久久777| 果冻传媒2021精品一区| 国产很色很黄很大爽的视频| 亚洲日韩av在线观看| 欧美熟妇性开放| 久久66热人妻偷产精品| 国产精品白浆无码流出视频| 日本乱理伦片在线观看中文| 伊人久久大香线蕉av五月天宝贝| 免费超爽大片黄| 人人爽人人爽人人片av东京热| 一本加勒比hezyo中文无码| 毛片无码国产| 久久99国产精品成人| 久久国产免费福利永久| 国产精品久久久久高潮| 成年女人18级毛片毛片免费| 色多多成视频人在线观看| 波多野结衣潮喷视频无码42| 少妇人妻精品一区二区三区| 亚洲精品国产av天美传媒| 国产最新av在线播放不卡| 在线看片福利无码网址| 极品尤物被啪到呻吟喷水| 最新国产精品精品视频| 人人添人人澡人人澡人人人人| 欧美色综合天天久久综合精品 | 丰满妇女强制高潮18xxxx| 99久久婷婷国产综合精品电影 | 成人无码av网站在线观看|