在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Thimet oligopeptidase (Thop1)

  • 中文名稱:
    大鼠Thop1重組蛋白
  • 貨號:
    CSB-YP023508RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Thop1重組蛋白
  • 貨號:
    CSB-EP023508RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Thop1重組蛋白
  • 貨號:
    CSB-EP023508RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Thop1重組蛋白
  • 貨號:
    CSB-BP023508RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Thop1重組蛋白
  • 貨號:
    CSB-MP023508RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Thop1; Thimet oligopeptidase; EC 3.4.24.15; Endo-oligopeptidase A; Endopeptidase 24.15; PZ-peptidase; Soluble metallo-endopeptidase
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-687
  • 氨基酸序列
    MKPPAACAGD VVDTVSPCST VNHLRWDLSA QQIRALTTQL IEQTKCVYDR VGAQDFEDVS YESTLKALAD VEVTYTVQRN ILDFPQHVSP NKDIRAASTE ADKKLSEFDV EMSMRQDVYQ RVVWLQEKIP KDSLKPEAAR YLERLIKLGR RNGLHLPQDT QEKIKNIKKR LSLLCIDFNK NLNEDTTFLP FTREELGGLP EDFLNSLEKT EDGKLKVTLK YPHYFPLLKK CHVPETRRLL EEAFNCRCKE ENCAILKELV SLRAQKSNLL GFRTHADYVL EMNMAKTSQT VATFLDELAR KLKPLGEQER AVILELKEAE CAKRGLPFDG RIHAWDMRYY MNQVEETRYR VDQNLLKEYF PMQVVTRGLL AIYQELLGLT FTLEEGAAAW HEDVRLYSVR DAASGEEIGK FYLDLYPREG KYGHAACFGL QPGCLRQDGS RQLAIAAMVA NFTKPTPDVP SLLQHDEVET YFHEFGHVMH QLCSQAEFAM FSGTHVERDF VEAPSQMLEN WVWEKEPLMR MSQHYRTGGE APEDLLEKLI KSRQANAGLF NLRQIVLAKV DQVLHTQTDV DPAEEYARLC QEILGVPATP GTNMPATFGH LAGGYDAQYY GYLWSEVYSM DMFHTRFKQE GVLSPKVGMD YRTSILRPGG SEDASTMLKQ FLGRDPKQDA FLLSKGLQVE GCEPPAC
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation.
  • 基因功能參考文獻:
    1. Coincubation of Kiss1 and EP24.15 demonstrated multiple cleavages of the peptide in vitro. immunohistochemistry indicated coexpression of EP24.15 and Kiss1, implicating that the regulation of Kiss1 by EP24.15 could occur in vivo. PMID: 26653570
    2. we show that Ang-(1-7) is the main metabolite of angiotensin I in rat hippocampi, and, strikingly, that thimet oligopeptidase is the main enzyme involved in the generation of Ang-(1-7). PMID: 24041943
    3. TOP changes in the brain could play important role in the balance of neuropeptide level correlated with cocaine effects. PMID: 22387539
    4. Data report mapping of the positions of the 224 surface residues that differ in sequence between thimet oligopeptidase and neurolysin onto the surface of the neurolysin crystal structure. PMID: 12192079
    5. this is the first evidence of an in vivo role for EP 24.15 in brain function, specifically in regulating alterations in microvessel permeability induced by exogenous bradykinin PMID: 12586639
    6. Analysis of transcription factors binding to promoter consensus sequences of the thimet oligopeptidase gene. Gene expression is differentially regulated in neuroendocrine and spermatid cell lines. PMID: 12911328
    7. data suggest that calcium may be an important modulator of ep24.15 cell function PMID: 15955058
    8. PTZ-induced seizures of the rats activates NMDA receptors, then decrease thimet oligopeptidase enzyme activity and immunoreactivity in hippocampal neurons. PMID: 15985312
    9. together, these data demonstrate that EP24.15/16 modulate intracellular, peptidergic signaling cascades through B2R in a physiologically relevant nociceptive system. PMID: 16515556
    10. increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load PMID: 18571100

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Peptidase M3 family
  • 組織特異性:
    Expressed abundantly in the testis. It is also found in the liver, lung and kidney.
  • 數據庫鏈接:


主站蜘蛛池模板: 99久热re在线精品视频| 娇妻玩4p被三个男人伺候电影 | 久久se精品一区精品二区| 国产亚洲精品久久久久久国| 牲交a欧美牲交aⅴ免费一| 欧美又粗又大aaa片| 国产亚洲精品久久久久久大师| 国产初高中生粉嫩无套第一次 | 人妻无码av中文系列久| 18禁黄网站禁片免费观看| 嫩b人妻精品一区二区三区| 亚洲欧美综合精品成人网| 亚洲精品国产高清一线久久| 久久久久黑人强伦姧人妻| 曰韩少妇内射免费播放| 小12萝裸体自慰出白浆| 久久精品第九区免费观看| 波多野结av衣东京热无码专区| 不卡无码av一区二区三区| 国产精品无码久久综合网| 人妻精品久久久久中文字幕69| 少妇荡乳情欲办公室456视频| 中文字幕乱码一区二区三区免费| 性按摩无码中文| 成年女人免费视频播放体验区| 国产熟妇勾子乱视频| 亚洲国产精品av在线播放| 成人18禁深夜福利网站app免费| 风韵丰满熟妇啪啪区老熟熟女| 久热这里只精品99国产6-99re视…| 国产农村乱辈无码| 免费人成自慰网站| 国产亚洲精品aaaaaaa片| 天堂亚洲2017在线观看| 久久久国产乱子伦精品作者| 久久久噜噜噜久久中文字幕色伊伊| 国产沙发午睡系列999| 一本一久本久a久久精品综合| 亚洲国产精品综合久久网络| 午夜精品久久久久9999| 亚洲中文字幕aⅴ天堂|