在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Synaptotagmin-4 (Syt4), partial

  • 中文名稱:
    大鼠Syt4重組蛋白
  • 貨號:
    CSB-YP023040RA1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Syt4重組蛋白
  • 貨號:
    CSB-EP023040RA1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Syt4重組蛋白
  • 貨號:
    CSB-EP023040RA1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Syt4重組蛋白
  • 貨號:
    CSB-BP023040RA1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Syt4重組蛋白
  • 貨號:
    CSB-MP023040RA1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Syt4
  • Uniprot No.:
  • 別名:
    Syt4; Synaptotagmin-4; Synaptotagmin IV; SytIV
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Synaptotagmin family member which does not bind Ca(2+). Involved in neuronal dense core vesicles (DCVs) mobility through its interaction with KIF1A. Upon increased neuronal activity, phosphorylation by MAPK8/JNK1 destabilizes the interaction with KIF1A and captures DCVs to synapses. Plays a role in dendrite formation by melanocytes.
  • 基因功能參考文獻:
    1. neuronal activity increased dense core vesicle capture via JNK-dependent phosphorylation of the S135 site of Synaptotagmin-4 PMID: 29166604
    2. The increased expression of Synaptotagmin IV in optic nerve crush eyes displays the possible neuroprotective effect of bone marrow mononuclear cell treatment PMID: 22695963
    3. Immunocytochemistry in rat chromaffin cells shows differential distribution of synaptotagmin-1, -4, -7, and -9. PMID: 21287204
    4. These data support an inhibitory effect of syt IV on release of vesicles and their transmitter content PMID: 20735850
    5. Rat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusion. PMID: 20688915
    6. The effects of syt IV on fusion pores are discussed in terms of structural models and kinetic mechanisms. PMID: 20303854
    7. present several lines of evidence showing that the Syt IV is normally localized in the Golgi or immature vesicles at the cell periphery and is sorted to fusion-competent mature dense-core vesicles in response to short nerve growth factor stimulation PMID: 12446703
    8. NMR analysis of Ca2+ binding to synaptotagmin 4 PMID: 15311271
    9. synaptotagmin IV protein trafficking from the Golgi to the cell periphery is regulated by forskolin PMID: 15496596
    10. Cells with overexpressed rat SytIV were unaltered in basal release probability, Ca2+ dependence of release, short-term plasticity, & fusion pore kinetics. Mutant Syt I (less Ca2+ affinity) reduced release probability & altered Ca2+ dependence of release. PMID: 16407532
    11. Downregulation of Syt IV reduced Ca(2+)-triggered exocytosis of dense core vesicles. Syt I silencing, however, had no effect on vesicular release. PMID: 18468511
    12. Given the neuroendocrine functions of the posterior pituitary, changes in Syt IV levels could be involved in endocrine transitions involving alterations in the release of the neuropeptides oxytocin and vasopressin PMID: 19136969
    13. Expression of Syt4 increases 9-fold at night in the rat pineal gland; treatment with dibutyryl cyclic AMP increases expresssion. PMID: 19103603

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane; Single-pass membrane protein.
  • 蛋白家族:
    Synaptotagmin family
  • 組織特異性:
    Widely expressed. Expressed in the brain. Expressed in pituitary gland, cerebellum, cortex, hypothalamus and hippocampus.
  • 數據庫鏈接:


主站蜘蛛池模板: 韩国三级中文字幕hd| 四虎国产精品永久在线无码| 久久久久久好爽爽久久| 性欧美丰满熟妇xxxx性仙踪林 | 成人毛片一区二区| 人妻少妇乱子伦无码专区| av综合网男人的天堂| 欧美中日韩免费观看网站| 免费的黄网站在线观看| 97在线精品视频免费| 免费人成又黄又爽的视频| 国精产品一区一区三区免费视频| 精品人妻伦九区久久aaa片| 人人玩人人添人人澡超碰偷拍| 亚洲国产日韩一区三区| 亚洲一区二区三区含羞草| 亚洲精品揄拍自拍首页一| 午夜精品久久久久久毛片| 亚洲欧洲日产国码久在线| 久热这里只有精品99| 欧美精品v国产精品v日韩精品| 久久99精品久久久久久| 亚洲乱码日产精品bd在线看| 国产成人a在线观看视频| 51国产偷自视频区视频| 国内揄拍国内精品少妇国语| 精品国产一区二区三区av片 | 中文字幕无码日韩中文字幕| 成人国产一区二区三区| 亚洲精品无码av黄瓜影视| 亚洲国产精品自在拍在线播放蜜臀 | 无码人妻一区二区中文| 强行无套内谢大学生初次| 亚洲精品国产品国语在线| 亚洲高清国产av拍精品青青草原| 国产精品无码久久综合网| 精品人伦一区二区三电影| 荡女精品导航| 日韩人妻无码免费视频一二区| 色综合伊人丁香五月桃花婷婷| 好湿好紧太硬了我太爽了视频|