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  4. Recombinant Rat Sulfotransferase family cytosolic 2B member 1 (Sult2b1)

Recombinant Rat Sulfotransferase family cytosolic 2B member 1 (Sult2b1)

  • 中文名稱：
    大鼠Sult2b1重組蛋白
  • 貨號：
    CSB-YP644962RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Sult2b1重組蛋白
  • 貨號：
    CSB-EP644962RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Sult2b1重組蛋白
  • 貨號：
    CSB-EP644962RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Sult2b1重組蛋白
  • 貨號：
    CSB-BP644962RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Sult2b1重組蛋白
  • 貨號：
    CSB-MP644962RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sult2b1
  • Uniprot No.：
  • 別名：
    Sult2b1; Sulfotransferase 2B1; EC 2.8.2.2; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2; Sulfotransferase family cytosolic 2B member 1; ST2B1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-340
  • 氨基酸序列
    MDGPQPPALW GSLENRVSEL SQKLQGEYFR YKGIPFPVGM YTPESLSLAE NTSNVRDDDI FIVTYPKSGT NWMIEIICLI LKDGDPSWIR SEPIWQRAPW CETTISAFSL PERPSPRLMC SHLPIELFTK AAFSSKAKVI YLGRNPRDVV VSLYYYSKIA VQLKDPGTPE QFLQNFLKGE VQFGSWFDHI KGWIRMRGRE NFLFITYEEL QQDLRGSVQL ICEFLGRPLG EEALSSVVAH SAFAAMKANN MSNYTLLPAS LLDHRQGAFL RKGISGDWKN HFTVAQSETF DQVYREQMHG LPSFPWDRSA EDGSPDGETE PSPSPSPGLA SDDPNPGSSQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfonates cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Conjugates efficiently cholesterol but has a greater affinity for pregnenolone sulfation. Does not show high activity with DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation.; Prefers pregnenolone over DHEA as a substrate and does not sulfate cholesterol.
  • 基因功能參考文獻：
    1. Since 1'-hydroxyestragole exposure readily produced DNA injury in B-13/H cells, these data suggest that cholangiocarcinomas generated in rats fed estragole may be dependent, in part, on SULT2B1 activation of the 1'-hydroxyestragole metabolite. PMID: 26739637
  • 亞細胞定位：
    Cytoplasm, cytosol. Microsome. Nucleus.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 組織特異性：
    Isoform 1 is expressed in skin and testis. Higher level of isoform 2 expressed in skin and intestine, moderate level in the kidney, low level in liver, stomach and placenta.
  • 數據庫鏈接：


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