在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat SNARE-associated protein Snapin (Snapin)

  • 中文名稱:
    大鼠Snapin重組蛋白
  • 貨號:
    CSB-YP021882RA
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Snapin重組蛋白
  • 貨號:
    CSB-EP021882RA
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Snapin重組蛋白
  • 貨號:
    CSB-EP021882RA-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Snapin重組蛋白
  • 貨號:
    CSB-BP021882RA
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Snapin重組蛋白
  • 貨號:
    CSB-MP021882RA
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Snapin
  • Uniprot No.:
  • 別名:
    Snapin; Bloc1s7; Snap25bp; SnapapSNARE-associated protein Snapin; Biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 subunit 7; Synaptosomal-associated protein 25-binding protein; SNAP-associated protein
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-136
  • 氨基酸序列
    AAAGSAAVS GAGTPVAGPT GRDLFAEGLL EFLRPAVQQL DSHVHAVRES QVELREQIDN LATELCRINE DQKVALDLDP YVKKLLNARR RVVLVNNILQ NAQERLRRLN HSVAKETARR RAMLDSGVYP PGSPSK
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
  • 基因功能參考文獻(xiàn):
    1. In pancreatic beta-cells the SNAP-25 accessory protein, snapin, C-terminal H2 domain binds SNAP-25 through its N-terminal Sn-1 domain. PMID: 26946359
    2. AC6-mediated inhibition of neurite outgrowth was reversed by the overexpression of Snap25 or a Snapin mutant that could not be phosphorylated. PMID: 21986494
    3. snapin may not have a role as a SNARE regulator in neurotransmitter release, as had been previously thought [SNAPIN] PMID: 15084593
    4. EBAG9 and Snapin have roles in controlling exocytosis processes PMID: 15635093
    5. our data suggest that snapin regulates dendrite number in developing neurons by modulating cypin-promoted microtubule assembly. PMID: 16120643
    6. Snapin binds to a 170-residue predicted ryanodine receptor cytosolic loop (RyR2 residues 4596-4765), containing a hydrophobic segment required for snapin interaction. PMID: 16723744
    7. activates alpha 1 Adrenergic Receptor and induces calcium influx through TRPC6 channels. PMID: 18480566

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Golgi apparatus membrane. Lysosome membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane.
  • 蛋白家族:
    SNAPIN family
  • 組織特異性:
    Strongly expressed in testis, spleen, kidney, liver and brain; lower expression in heart, fat and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 久久99精品久久久久婷婷暖| 人妻夜夜爽天天爽一区| 国产aⅴ爽av久久久久久| 日本少妇无码精品12p| 青青草免费国产线观720| 久久天天躁夜夜躁狠狠躁| 99久久精品视香蕉蕉| 草草久久久无码国产专区| 国产午夜视频在线观看| 亚洲精品久久久久久下一站| 国产午夜理论片不卡| 久久久www成人免费看片| 久久99er6热线精品首页| 国产精品久久久久久影视不卡| 国产国拍亚洲精品av在线| 日本午夜免费福利视频| 人与禽性视频77777| 免费全部高h视频无码| 天天av天天av天天透| 极品美女扒开粉嫩小泬图片| 波多野结衣av无码久久一区| 刺激性视频黄页| 无套内谢少妇毛片aaaa片免费| 人妻人人看人妻人人添| 毛片免费视频在线观看| 欧美人与动性xxxxx杂| 熟妇人妻无乱码中文字幕真矢织江| 久久久久久成人综合网| 一区二区三区乱码在线 | 欧洲| 啪啪无码人妻丰满熟妇| 西西人体www大胆高清| 国产草莓精品国产av片国产| 亚洲综合无码av一区二区三区| 清纯小美女主播流白浆| 久久久久久午夜成人影院| 亚洲妇熟xxxx妇色黄| 亚洲国产欧美在线人成大黄瓜 | 国产福利一区二区三区在线视频| 邻居少妇张开腿让我爽了在线观看 | 重口sm一区二区三区视频| 中文字幕日韩人妻不卡一区 |