在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Regulator of G-protein signaling 4 (Rgs4)

Recombinant Rat Regulator of G-protein signaling 4 (Rgs4)

  • 中文名稱(chēng)：
    大鼠Rgs4重組蛋白
  • 貨號(hào)：
    CSB-YP019656RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    大鼠Rgs4重組蛋白
  • 貨號(hào)：
    CSB-EP019656RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    大鼠Rgs4重組蛋白
  • 貨號(hào)：
    CSB-EP019656RA-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    大鼠Rgs4重組蛋白
  • 貨號(hào)：
    CSB-BP019656RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    大鼠Rgs4重組蛋白
  • 貨號(hào)：
    CSB-MP019656RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Rgs4
  • Uniprot No.：
  • 別名：
    Rgs4; Regulator of G-protein signaling 4; RGP4; RGS4
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-205
  • 氨基酸序列
    MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHSSSHS KKDKVVTCQR VSQEEVKKWA ESLENLINHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS VQATKEVNLD SCTREETSRN MLEPTITCFD EAQKKIFNLM EKDSYRRFLK SRFYLDLTNP SSCGAEKQKG AKSSADCTSL VPQCA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
  • 基因功能參考文獻(xiàn)：
    1. After alphao dissociates from MOR, RGS4 remains bound to the C-terminal region of MOR PMID: 26119705
    2. Data suggest that RGS4 proteins play an important pathophysiological role in the development and expression of l-DOPA-induced dyskinesia PMID: 24969021
    3. partial agonism of the M2 muscarinic receptor is regulated by the RGS4-mediated inhibition of G-protein signalling PMID: 24421355
    4. Tra2beta regulates the expression of RGS4 gene and is induced by morphine. PMID: 23977258
    5. data demonstrate that RGS4 in the dorsal striatum attenuates amphetamine-induced ERK signaling and decreases the behavioral efficacy of acute amphetamine likely by limiting mGluR5 function PMID: 22193724
    6. The functional activity and protein binding partners of a candidate AP-1R sequence were determined for a novel FRA-2-repressed gene, Rgs4. PMID: 21367864
    7. A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription. PMID: 20630860
    8. RGS4 was up-regulated only when RGS2 was down-regulated in the striatum after intracerebroventricular injection of forskolin PMID: 12603835
    9. up-regulation of RGS4 expression may contribute to changes in pain signal processing that lead to the development of hyperalgesia, and further affect its modulation by morphine. PMID: 12604710
    10. RGS4 is expressed at high levels in C-fiber primary sensory neurons in the adult rat dorsal root ganglion (DRG) and sciatic nerve transection results in a substantial down regulation of this transcript. PMID: 14550772
    11. Amphetamine may disinhibit RGS4-sensitive guanine nucleotide-binding protein alpha-subunit i- and/or q-coupled signaling pathways and favor mechanisms that counterbalance D(1) receptor stimulation. PMID: 16539683
    12. These observations suggest that RGS4-dependent attenuation of interneuronal autoreceptor signaling is a major factor in the elevation of striatal acetylcholine release in Parkinson disease. PMID: 16699510
    13. Expression of RGS4 mRNA was not affected by the corticosterone injection, neither in the CA1 area nor in other hippocampal subregions. PMID: 17060050
    14. study revealed an important coupling of RGS4 to serotonin signaling in cortical neurons and provided a molecular and cellular mechanism underlying the potential involvement of RGS4 in the pathophysiology of schizophrenia. PMID: 17220354
    15. Changes in RGS4 mRNA levels might signal abnormal receptor G-protein coupling that impacts cocaine seeking. PMID: 17632279
    16. After 2 days of aortic banding-induced hypertrophy, thoracic aorta lost expression of Rgs4, it returned to normal at 1 week and increased many fold at 28 days, indicating that RGS expression and function correlate with vascular remodeling. PMID: 18207159

    顯示更多

    收起更多

  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 久久人人爽人人爽人人片av| 久久人搡人人玩人妻精品| 日韩一区精品视频一区二区| 人妻在线日韩免费视频| 日本伊人色综合网| 国产亚洲综合区成人国产| 先锋人妻无码av电影 | 国内精品伊人久久久久av| 亚洲 综合 欧美 动漫 丝袜| 亚洲欧美日韩另类丝袜一区| 亚洲爆乳少妇无码激情| 麻豆乱码国产一区二区三区| 久久人人做人人妻人人玩精品hd| 亚洲精品综合一区二区三| 和黑人邻居中文字幕在线| ā片在线观看免费观看| 可以看三级的网站| 无码国产偷倩在线播放| 久久精品私人影院免费看| 麻花传媒mv国产免费观看视频| 扒开双腿疯狂进出爽爽爽| 亚洲一二三四2021不卡| 欧美精品黑人粗大免费| 精品一二三区久久aaa片| 成人免费xxxxx在线观看| av中文字幕潮喷人妻系列| 国产成人av一区二区三区无码| 好了av第四综合无码久久| 无套内射在线无码播放| 国产国拍精品av在线观看| 久久精品国产男包| 麻豆精品国产熟妇aⅴ一区| 欧美老熟妇xb水多毛多| 18禁无遮挡无码网站免费| 欧美国产亚洲日韩在线二区| 97久久人人超碰超碰窝窝| 久久无码av三级| 国产丝袜在线精品丝袜不卡| 嫩草欧美曰韩国产大片| 色欲色香天天天综合无码www| 99在线精品一区二区三区|