在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Regulator of G-protein signaling 2 (Rgs2)

Recombinant Rat Regulator of G-protein signaling 2 (Rgs2)

  • 中文名稱：
    大鼠Rgs2重組蛋白
  • 貨號(hào)：
    CSB-YP878054RA
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Rgs2重組蛋白
  • 貨號(hào)：
    CSB-EP878054RA
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Rgs2重組蛋白
  • 貨號(hào)：
    CSB-EP878054RA-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Rgs2重組蛋白
  • 貨號(hào)：
    CSB-BP878054RA
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Rgs2重組蛋白
  • 貨號(hào)：
    CSB-MP878054RA
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Rgs2; Regulator of G-protein signaling 2; RGS2
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-211
  • 氨基酸序列
    MQSAMFLAVQ HDCVPMDKSA GNGPKVEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQTFI KPSPEEALLW AEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
  • 基因功能參考文獻(xiàn)：
    1. These results suggest that Dahl S rats exhibit a blunted RGS2 response to Ang-II, and this blunted response may be partially responsible for the susceptibility to renal injury in Dahl S rats. PMID: 26606876
    2. The protective effects of RGS2 in cardiac hypertrophy may derive at least in part from its ability to govern protein synthesis. PMID: 24576550
    3. RGS2 functions on a daily basis to negatively modulate melatonin production PMID: 23523917
    4. Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 PMID: 22057271
    5. Ischemic stress increases RGS2 expression and that this condition contributes to enhanced apoptosis in C6 cells and primary astrocytes. PMID: 20032508
    6. Analysis of regulator of G-protein signaling-2 (RGS-2) expression and function in osteoblastic cells. PMID: 11968023
    7. RGS2 is expressed in the neocortex, piriform cortex, caudate-putamen, septum, hippocampus, and locus coeruleus. RGS2 is not involved in the hypersensitization of postsynaptic dopamine receptors observed after lesion of the nigrostriatal pathway. PMID: 12207953
    8. D1 and D2 receptors exert opposite effects on RGS2 expression, as they do on cAMP levels, suggesting a cAMP-mediated transcription of RGS2 in the corpus striatum PMID: 12603835
    9. Sex steroids (progesterone) and presence of conceptus play role in regulation of myometrial RGS2. Myometrial RGS2 is elevated when uterus is quiescent. Down-regulation of RGS2 at end of pregnancy may be related to timing of parturition. PMID: 12712095
    10. Regulation of RGS-2 may constitute a novel mechanism by which steroids modulate signaling via the PTH/PTHrP receptor and other G protein-coupled receptors in bone. PMID: 12746312
    11. group VIA phospholipase A2 (iPLA2beta) plays a pivotal role in Ang II-induced RGS2 mRNA up-regulation in vascular smooth muscle cells PMID: 17613534
    12. After 2 days of aortic banding-induced hypertrophy, thoracic aorta lost expression of Rgs2 , it returned to normal at 1 week and increased many fold at 28 days, indicating that RGS expression and function correlate with vascular remodeling. PMID: 18207159
    13. S1P induces RGS2 and RGS16 mRNA expression but uses distinct S1P receptor subtypes and signalling pathways to regulate expression of these RGS proteins PMID: 19374869

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane. Cytoplasm. Nucleus, nucleolus.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 国产又色又爽又黄的| 国产良妇出轨视频在线观看| 日韩不卡1卡2卡三卡2021免费| 亚洲精品黑牛一区二区三区 | 亚洲午夜高清国产拍| 少妇高潮太爽了在线视频| 欧美成a人片在线观看久| 无遮无挡爽爽免费毛片| 中文字幕无码免费不卡视频| 国产美女亚洲精品久久久| 亚洲 卡通 欧美 制服 中文| 中文字幕日韩人妻无码| 日日噜噜噜噜夜夜爽亚洲精品| 亚洲精品久久区二区三区蜜桃臀| 亚洲人成无码区在线观看 | 97婷婷狠狠成为人免费视频| 国产麻豆剧果冻传媒白晶晶| 欧美巨大另类极品videosbest | 少妇人妻邻居| 国产精品香港三级国产av| 无码av动漫精品一区二区免费| 女人与公拘交酡全过程| 日本免费高清一本视频| 国产精品无码一区二区三区电影| 免费看成人欧美片爱潮app| 国产精品a国产精品a手机版| 女人19水真多免费毛片| 97高清国语自产拍| 欧美老人巨大xxxx做受视频| 亚洲精品无码av人在线观看| 成人啪精品视频网站午夜| 国农村精品国产自线拍| 日本边添边摸边做边爱的网站| 老湿机69福利区无码| 国产精品96久久久久久av网址| 噜噜高清欧美内射短视频| 动漫av纯肉无码av在线播放| 成在人线av无码免观看麻豆| 无码国产片观看| 精品久久久久久久无码| 国产在线精品一区二区不卡麻豆|