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  4. Recombinant Rat Pancreatic secretory trypsin inhibitor (Spink1)

Recombinant Rat Pancreatic secretory trypsin inhibitor (Spink1)

  • 中文名稱：
    大鼠Spink1重組蛋白
  • 貨號：
    CSB-YP022575RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Spink1重組蛋白
  • 貨號：
    CSB-EP022575RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Spink1重組蛋白
  • 貨號：
    CSB-EP022575RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Spink1重組蛋白
  • 貨號：
    CSB-BP022575RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Spink1重組蛋白
  • 貨號：
    CSB-MP022575RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Spink1
  • Uniprot No.：
  • 別名：
    Spink1; Serine protease inhibitor Kazal-type 1; Cholecystokinin-releasing peptide; Monitor peptide; Pancreatic secretory trypsin inhibitor; PSTI-I
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    19-79
  • 氨基酸序列
    GN PPAEVNGKTP NCPKQIMGCP RIYDPVCGTN GITYPSECSL CFENRKFGTS IHIQRRGTC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
  • 基因功能參考文獻：
    1. This study created a novel mouse model of mtDNA depletion by expressing relatively low levels of mito-PstI in CNS neurons, which leads to a chronic OXPHOS deficiency. PMID: 21734281
    2. severity of chronic pancreatitis and pancreatic fibrosis is significantly reduced in mice expressing rat PSTI-I; propose that endogenous pancreatic trypsin inhibitors play a protective role in the pancreatic response to repeated injurious events PMID: 19904222
    3. dual function: monitoring protein in gut due to its 'moderate' affinity for trypsin and a protective role in pancreas PMID: 12771515
    4. Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin. PMID: 18054043
    5. Caltrin protein modulates the acrosomal exocytosis during sperm capacitation. PMID: 18550793

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  • 亞細胞定位：
    Secreted.
  • 數據庫鏈接：


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