在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Neuropeptide S (Nps)

  • 中文名稱:
    大鼠Nps重組蛋白
  • 貨號:
    CSB-YP016026RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Nps重組蛋白
  • 貨號:
    CSB-EP016026RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Nps重組蛋白
  • 貨號:
    CSB-EP016026RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Nps重組蛋白
  • 貨號:
    CSB-BP016026RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Nps重組蛋白
  • 貨號:
    CSB-MP016026RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Nps
  • Uniprot No.:
  • 別名:
    Nps; Neuropeptide S
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Cytoplasmic domain
  • 表達區域:
    70-89
  • 氨基酸序列
    S FRNGVGSGVK KTSFRRAKQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations.
  • 基因功能參考文獻:
    1. Neuropeptide S (NPS) increases motor activity and thermogenesis in the rat through sympathetic activation. These results suggest that NPS contributes to the regulation of the sympathetic nervous system. PMID: 28433253
    2. Intracerebroventricular (i.c.v.) NPS evoked a significant somatodendritic release of oxytocin within the paraventricular nucleus. The anxiolytic effects of NPS within the hypothalamic PVN are mediated via actions on local oxytocin neurons in male Wistar rats. PMID: 29118105
    3. Our study identified a protective role for NPS in amygdala against the development of NP, possibly attributing to its anti-inflammatory activity and inhibition of spinal microglia and astrocytes PMID: 27224019
    4. Present results suggest a selective activation of one of the three neuropeptide S-expressing neuron clusters as well as release of neuropeptide S in distinct forebrain regions after sleep deprivation. PMID: 26462664
    5. Single-dose and long-term (4 months) olanzapine treatment led to the upregulation of NPS expression in the rat hypothalamus. PMID: 26227793
    6. Results suggest that excitatory and inhibitory actions by the neuropeptide S system are integral to the depression in learned helplessness animals PMID: 25986404
    7. NPS activates histaminergic and orexinergic neurons, thereby promoting wakefulness. PMID: 22300983
    8. emotional stress-induced release of neuropeptide S in the amygdala supporting a functional role of endogenous NPS in stress/anxiety-related phenomena. PMID: 21861171
    9. data suggest a role for neuropeptide S in the modulation of ethanol drinking and possibly anxiety-like behavior in rats selectively bred for high alcohol drinking. PMID: 18564106
    10. These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats. PMID: 21452235
    11. NPS blocked cue-induced cocaine seeking, indicating a role for this system in the pathophysiology of drug relapse PMID: 20974945
    12. The results suggest that neuropeptide S mitigates spatial memory impairment in rats induced by 72-h REM sleep deprivation, possibly through activating cAMP-response element binding protein phosphorylation in the hippocampus. PMID: 20495497

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 組織特異性:
    Expressed in mammary, salivary and thyroid gland. Expressed in the brain, in a cluster of cells located between the locus coeruleus (LC) and Barrington's nucleus, as well as in few cells of the dorsomedial hypothalamic nucleus and the amygdala.
  • 數據庫鏈接:


主站蜘蛛池模板: 色橹橹欧美在线观看视频高清 | 日韩精品无码一本二本三本| 男女啪啪免费观看的网址| 无码人妻天天拍夜夜爽| 麻豆妓女爽爽一区二区三| 精产国品一二三产区m553麻豆| 西西444www无码大胆| 日韩欧美亚洲综合久久影院d3| 一本一道色欲综合网| 宅男色影视亚洲人在线| 亚洲线精品一区二区三区影音先锋| 国模小黎自慰gogo人体| 中文字幕无码免费不卡视频| 国产成人无码18禁午夜福利网址| 久久精品国产只有精品66| 久久国产精品久久久久久| 性欧美大胆免费播放| 人妻aⅴ中文字幕| 亚洲精品无码不卡在线播放he| 久久国内精品自在自线400部| 亚洲精品国产suv一区88| 亚洲va久久久噜噜噜久久天堂| 精品日产卡一卡二卡麻豆| 无码av高潮喷水无码专区线| 偷国产乱人伦偷精品视频| 亚洲中文字幕无码一区在线| 欧美极品video粗暴| 日本国产成人国产在线播放| 国产精品天天看特色大片| 狠狠色综合激情丁香五月| 精品无人区一区二区三区| 老司机久久一区二区三区| 欧美黑人xxxx性高清版| 欧美乱大交xxxxx潮喷l头像| 欧美变态暴力牲交videos| 亚洲精品日韩一区二区小说| 性色av一二三天美传媒| 国产女人18毛片水真多18精品| 中国女人和老外的毛片| 日本少妇高潮喷水免费可以看| 天天综合色天天综合色hd|