在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1)

Recombinant Rat Na (+)/H (+) exchange regulatory cofactor NHE-RF1 (Slc9a3r1)

  • 中文名稱：
    大鼠Slc9a3r1重組蛋白
  • 貨號：
    CSB-YP888318RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Slc9a3r1重組蛋白
  • 貨號：
    CSB-EP888318RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Slc9a3r1重組蛋白
  • 貨號：
    CSB-EP888318RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Slc9a3r1重組蛋白
  • 貨號：
    CSB-BP888318RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Slc9a3r1重組蛋白
  • 貨號：
    CSB-MP888318RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Slc9a3r1; Nherf; Nherf1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; NHERF-1; Ezrin-radixin-moesin-binding phosphoprotein 50; EBP50; Regulatory cofactor of Na(+)/H(+) exchanger; Sodium-hydrogen exchanger regulatory factor 1; Solute carrier family 9 isoform A3 regulatory factor 1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-356
  • 氨基酸序列
    SADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDEQLK KLGVPIREEL LRAQEKSEHT EPPAAADTKK AGDQNEAEKS HLERCELRPR LCTMKKGPNG YGFNLHSDKS KPGQFIRAVD PDSPAEASGL RAQDRIVEVN GVCMEGKQHG DVVSAIKAGG DEAKLLVVDK ETDEFFKKCR VTPSQEHLDG PLPEPFSNGE IQKENSREAL VEPASESPRP ALARSASSDT SEELNAQDSP KRHDSTEPSS TSSSSDPILD FNISLAVAKE RAHQKRSSKR APQMDWSKKN ELFSNL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules.
  • 基因功能參考文獻：
    1. The purpose of this study was to clarify the assembly of taurine transporter (TauT/Slc6a6) and PSD-95/Disc-large/Zo-1 (PDZ) domain of Slc9a3r1 as a regulatory mechanism of Slc6a6-mediated GABA transport activity PMID: 29491210
    2. These results suggest that decreased renal NHERF-1 expression contributes to the impaired dopamine-mediated inhibition of NKA in PTCs from animal models of hypertension. PMID: 28515088
    3. that NHERF1 associates with NaPi-2b in enterocytes and regulates NaPi-2b adaptation. PMID: 22904329
    4. EBP50 is involved in the regulation of vascular smooth muscle cell migration and cytokinesis PMID: 21598299
    5. The cochlear localization of NHERF scaffolds suggests that they play important roles in the developmental regulation of ion transport, homeostasis, and auditory neurotransmission. PMID: 16160858
    6. EBP50 redistribute apically in rat uterine epithelial cells at the time of implantation and in response to cell contact.( PMID: 21120533
    7. NHERF1 bound to an internal PDZ binding motif in megalin and that a loss of a single threonine residue abolished the interaction between megalin and NHERF1. PMID: 21325834
    8. In uterus, NHERF1 was expressed in the apical region of the luminal epithelium and glands in all stages of the estral cycle, and in both colon and uterus, the expression was independent of the proliferation status PMID: 21079987
    9. the activation of ROCK leads to the binding of moesin to EBP50, which interacts with several components of the cytoskeleton, resulting in a decrease in the contractile response. PMID: 20926777
    10. Results indicated that PKC-induced phosphorylation of EBP50 occurred on the Ser337/Ser338 residue within the carboxyl-tail domain of the protein and truncation of Ser337/Ser338 also diminished PKC-induced oligomerization of EBP50. PMID: 15878350
    11. CFTR is an important regulator of AQP9 and the interaction between AQP9, NHERF1, and CFTR may facilitate the activation of AQP9 by cAMP. PMID: 18055461

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Apical cell membrane. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus. Endomembrane system; Peripheral membrane protein.
  • 數據庫鏈接：


主站蜘蛛池模板： 成人影院yy111111| 精品乱码无人区一区二区| 中文字幕丰满乱孑伦无码专区| 国产成人小视频| 妺妺窝人体色777777| 四虎影在永久在线观看| 中国熟妇内谢69xxxxx| 动漫无遮挡h纯肉亚洲资源大片| 日本人与黑人做爰视频网站| 成在人线av无码免费| 亚洲337少妇裸体艺术| 99久久免费国产精品四虎| 精品无码国模私拍视频| 裸身美女无遮挡永久免费视频| 无码不卡av东京热毛片| 51久久成人国产精品麻豆| 亚洲另类自拍丝袜第五页| 国产农村乱辈无码| 国产成人久久777777| 精品深夜av无码一区二区| 欧美交换配乱吟粗大25p| 色猫咪免费人成网站在线观看| 国产精品第一区揄拍无码| a在线视频v视频| 精品久久久久久成人av | 中文字幕无码日韩专区| 国产欧美日韩精品专区| 精品欧美一区二区三区久久久 | 日韩午夜理论免费tv影院| 无码专区6080yy国产电影| 亚洲欧美国产精品久久| 国精产品999国精产| 亚洲龙腾成小说人网| 国产成人亚洲精品无码青青草原 | 国产精品va无码一区二区| 97国产精品人妻无码久久久| 国产成人亚洲综合青青| 一道久在线无码加勒比| 荫蒂被男人添的好舒服爽免费视频| 国产成人精品成人a在线观看 | 欧亚乱熟女一区二区在线|