在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Lysine-specific demethylase 8 (Jmjd5)

Recombinant Rat Lysine-specific demethylase 8 (Jmjd5)

  • 中文名稱：
    大鼠Kdm8重組蛋白
  • 貨號：
    CSB-YP677704RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Kdm8重組蛋白
  • 貨號：
    CSB-EP677704RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Kdm8重組蛋白
  • 貨號：
    CSB-EP677704RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Kdm8重組蛋白
  • 貨號：
    CSB-BP677704RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Kdm8重組蛋白
  • 貨號：
    CSB-MP677704RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Kdm8
  • Uniprot No.：
  • 別名：
    Kdm8; Jmjd5; Bifunctional peptidase and arginyl-hydroxylase JMJD5; EC 1.14.11.-; EC 3.4.-.-; JmjC domain-containing protein 5; Jumonji C domain-containing protein 5; L-arginine; 3R)-hydroxylase KDM8
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-414
  • 氨基酸序列
    MSEDTTEPLV GPSTLWKDLR ALLPDTEEEL KLDLSEKVDR SMATLLRQAL GLFYEGRWQK CLQASEAVLD YSWEKLNTGP WRDVDKEWRR VYSFGCLLKT LCLCQAPQKA TAVAEALRVC DMGLLMGAAI LGDILLKVAT VLQTHLLPRK QPACGPHQDQ PATKKAKHDA SSTPDVVLDR EVPRLRCPPL QHFKKHFLVP GRPVILEGVA DHWPCMKKWS LQYIQEIAGC RTVPVEVGSR YTDEDWSQTL MTVNEFIHKY ILSEAKDVGY LAQHQLFDQI PELKQDISIP DYCCLGNGEE EEITINAWFG PQGTISPLHQ DPQQNFLVQV LGRKYIRLYS PQESEAVYPH ETHILHNTSQ VDVENPDLEK FPKFTEAPFL SCILSPGDTL FIPAKYWHYV RSLDLSFSVS FWWS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monoxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Upon DNA damage, cleaves the N-terminal tail of histone H3 at monomethylated lysine residues, preferably at monomethylated 'Lys-9' (H3K9me1). The histone variant H3F3A is the major target for cleavage. Additionnally, acts as Fe(2+) and 2-oxoglutarate-dependent monoxygenase, catalyzing (R)-stereospecific hydroxylation at C-3 of 'Arg-137' of RPS6 and 'Arg-141' of RCCD1, but the biological significance of this activity remains to be established. Regulates mitosis through different mechanisms: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with RCCD1. Possibly together with RCCD1, is involved in proper mitotic spindle organization and chromosome segregation. Negatively regulates cell cycle repressor CDKN1A/p21, which controls G1/S phase transition. Required for G2/M phase cell cycle progression. Regulates expression of CCNA1/cyclin-A1, leading to cancer cell proliferation. Also, plays a role in regulating alpha-tubulin acetylation and cytoskeletal microtubule stability involved in epithelial to mesenchymal transition. Regulates the circadian gene expression in the liver. Represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer in a catalytically-independent manner. Negatively regulates the protein stability and function of CRY1; required for AMPK-FBXL3-induced CRY1 degradation.
  • 亞細胞定位：
    Nucleus. Chromosome.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲国产精久久久久久久| 亚洲性人人天天夜夜摸18禁止| 久九九久视频精品免费| 国产日产久久高清欧美一区| 欧美熟妇xxxxx欧美老妇不卡 | 无码人妻精品中文字幕免费东京热| 国产麻豆成人精品av| 九九久久精品免费观看| 午夜高清国产拍精品| 久久久久高潮综合影院| 人妻无码中文专区久久app| 日日碰狠狠躁久久躁96| 国产超级va在线观看视频| 极品少妇xxxx精品少妇偷拍| 无码人妻一区二区三区一| 97人人添人澡人人爽超碰| 人妻体验按摩到忍不住哀求继续 | 最近中文字幕免费mv在线| av中文字幕无码免费看| 人妻体内射精一区二区三区| 国产精品多p对白交换绿帽| 国产成人精品a∨一区二区| 极品少妇被猛的白浆直喷白浆| 无码免费毛片手机在线无卡顿| 青青青青国产免费线在线观看| 少妇高潮太爽了在线观看欧美| 色一情一乱一伦麻豆| 丰满多毛的大隂户毛茸茸| 久久人人爽av亚洲精品| 永久免费观看国产裸体美女| 亚洲欧美一区二区成人片| 国产成人无码免费视频麻豆| 人成午夜免费视频无码| 成人伊人精品色xxxx视频| 99热门精品一区二区三区无码| 成人无码一区二区三区网站 | 美女露全乳无遮掩视频| 国产美女爽到喷出水来视频| 国产精品久久久久无码av1| 2019nv天堂香蕉在线观看| 日韩精品无码中文字幕一区二区|