在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Intersectin-1 (Itsn1), partial

Recombinant Rat Intersectin-1 (Itsn1), partial

  • 中文名稱：
    大鼠Itsn1重組蛋白
  • 貨號：
    CSB-YP893434RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Itsn1重組蛋白
  • 貨號：
    CSB-EP893434RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Itsn1重組蛋白
  • 貨號：
    CSB-EP893434RA-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Itsn1重組蛋白
  • 貨號：
    CSB-BP893434RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Itsn1重組蛋白
  • 貨號：
    CSB-MP893434RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Itsn1
  • Uniprot No.：
  • 別名：
    Itsn1; Ehsh1; Itsn; Intersectin-1; EH domain and SH3 domain regulator of endocytosis 1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex. Plays a role in the assembly and maturation of clathrin-coated vesicles. Recruits FCHSD2 to clathrin-coated pits. Involved in endocytosis of activated EGFR, and probably also other growth factor receptors. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Promotes ubiquitination and subsequent degradation of EGFR, and thereby contributes to the down-regulation of EGFR-dependent signaling pathways. In chromaffin cells, required for normal exocytosis of catecholamines. Required for rapid replenishment of release-ready synaptic vesicles at presynaptic active zones. Inhibits ARHGAP31 activity toward RAC1.; Plays a role in synaptic vesicle endocytosis in brain neurons.
  • 基因功能參考文獻(xiàn)：
    1. The intersectin1-L protein was primarily expressed in neurons in brain tissue. Its expression was remarkably increased in patients with refractory epilepsy and in epilepsy model rats. PMID: 25783631
    2. intersectin is an endocytic scaffold with a role in fast neurotransmitter release, which may be of prime importance for information processing in the brain PMID: 23633571
    3. Intersectin-1L and beta-Pix, play essential roles in neuroendocrine exocytosis by controlling the activity of Cdc42 and Rac1, respectively. PMID: 21088884
    4. intersectin-l is indeed an important regulator of constitutive endocytosis and neuronal development but that it is not a prominent player in the regulated endocytosis of SVs. PMID: 19258322
  • 亞細(xì)胞定位：
    Endomembrane system. Cell junction, synapse, synaptosome. Cell projection, lamellipodium. Cell membrane. Membrane, clathrin-coated pit. Recycling endosome. Endosome. Cytoplasmic vesicle.; [Isoform 2]: Cytoplasm. Nucleus envelope.
  • 組織特異性：
    Detected in brain, spleen, lung, liver and heart (at protein level). Ubiquitous. Detected in brain, spleen, lung, liver, skeletal muscle and kidney.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 好男人社区在线www| 亚洲精品午夜理伦不卡在线观看| 欧美成人高清视频a在线看| 国产一区二区三区内射高清| 黑人大群体交免费视频| 中文字幕乱码一区av久久| 伊人久久大香线蕉aⅴ色| 国产亚洲精品a在线观看下载| 777久久精品一区二区三区无码| 日韩久久无码免费毛片软件| 国产美女精品自在线拍免费| 亚洲欧洲日本综合aⅴ在线| 高清不卡一区二区三区| 亚洲熟妇无码八av在线播放| 国产在线午夜不卡精品影院 | 97色偷偷色噜噜狠狠爱网站| 人与禽性视频77777| 蜜芽av无码精品国产午夜| 国产精品久久毛片| 白又丰满大屁股bbbbb| 风韵人妻丰满熟妇老熟女| 免费午夜理论不卡| 亚洲爆乳少妇无码激情| 亚洲精品久久区二区三区蜜桃臀| 无码一区二区三区老色鬼| 欧洲亚洲色视频综合在线| 国产一区二区三区小说| 人妻洗澡被强公日日澡电影 | 精品国偷自产在线视频99| 免费三级网站| 狠狠做深爱婷婷久久综合一区| 77se77亚洲欧美在线| 国内揄拍国内精品少妇| 日日噜噜噜夜夜爽爽狠狠视频| 华人在线亚洲欧美精品| 精品国产在天天在线观看| 99国产精品99久久久久久| 精品国产乱码久久久久app下载| 99久久超碰中文字幕伊人| 国产高潮视频在线观看| 九九综合九色综合网站|