在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Interleukin-17F (Il17f)

  • 中文名稱:
    大鼠Il17f重組蛋白
  • 貨號:
    CSB-YP685584RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Il17f重組蛋白
  • 貨號:
    CSB-EP685584RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Il17f重組蛋白
  • 貨號:
    CSB-EP685584RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Il17f重組蛋白
  • 貨號:
    CSB-BP685584RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Il17f重組蛋白
  • 貨號:
    CSB-MP685584RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Il17fInterleukin-17F; IL-17F
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    29-161
  • 氨基酸序列
    RR NPKVGLSALQ KAGNCPPLED NSVRVDIRIF NQNQGISVPR DFQNRSSSPW DYNITRDPDR FPSEIAEAQC RHSGCINAQG QEDGSMNSVP IQQEILVLRR EPQGCSNSFR LEKMLIKVGC TCVTPIVHHA A
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains. This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation. IL17A-IL17F is primarily involved in host defense against extracellular bacteria and fungi by inducing neutrophilic inflammation. As signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites. Stimulates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers. IL17F homodimer can signal via IL17RC homodimeric receptor complex, triggering downstream activation of TRAF6 and NF-kappa-B signaling pathway. Via IL17RC induces transcriptional activation of IL33, a potent cytokine that stimulates group 2 innate lymphoid cells and adaptive T-helper 2 cells involved in pulmonary allergic response to fungi. Likely via IL17RC, promotes sympathetic innervation of peripheral organs by coordinating the communication between gamma-delta T cells and parenchymal cells. Stimulates sympathetic innervation of thermogenic adipose tissue by driving TGFB1 expression. Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes.
  • 基因功能參考文獻:
    1. Increased RORgammat and IL-17F levels contribute to Spontaneously Hypertensive Rat hypertension and might be therapeutic targets PMID: 28093217
    2. important mediator of increased endothelial permeability PMID: 19577259
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    IL-17 family
  • 數據庫鏈接:


主站蜘蛛池模板: 中文字幕无码免费不卡视频| 波多野结衣中文字幕一区二区三区 | 色欲天天天无码视频| 九九久久精品国产| 中文字幕人成乱码在线观看| 久久久久香蕉国产线看观看伊 | 久久亚洲国产成人精品无码区 | 亚洲 制服丝袜 中文字幕 在线| 久久丫精品系列| 性xxxx搡xxxxx搡欧美| 男女同房做爰爽免费| 欧美性猛交xxxxx按摩欧美| 中文字幕人妻丝袜二区| 日本最新免费二区三区| 综合激情丁香久久狠狠| 欧美人与动性xxxxbbbb| 熟女视频一区二区在线观看| 国产精品熟妇视频国产偷人| 成人无码嫩草影院| 天天综合色天天综合色hd| 国产熟妇久久777777| 欧美高清精品一区二区| 中文字幕av伊人av无码av狼人| 国产综合色在线精品| 婷婷五月综合色视频| 久久久久久久岛国免费观看 | 日本丰满熟妇videossex8k| www亚洲精品久久久| 午夜成人亚洲理论片在线观看| 国产成人精品免高潮在线观看| 国产蜜臀av在线一区尤物| 白嫩无码人妻丰满熟妇啪啪区百度| 欧洲国产精品无码专区影院 | 美女扒开屁股让男人桶| 亚洲国产欧美在线人成人| 亚洲欧洲日本综合aⅴ在线| 情侣作爱视频网站| 欧美不卡一卡二卡三卡| 国产午夜福利小视频合集| 中国极品少妇xxxxx| 国精品人妻无码一区二区三区d3|