在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Insulin-like growth factor-binding protein 1 (Igfbp1)

Recombinant Rat Insulin-like growth factor-binding protein 1 (Igfbp1)

  • 中文名稱：
    大鼠Igfbp1重組蛋白
  • 貨號：
    CSB-YP011095RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Igfbp1重組蛋白
  • 貨號：
    CSB-EP011095RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Igfbp1重組蛋白
  • 貨號：
    CSB-BP011095RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Igfbp1重組蛋白
  • 貨號：
    CSB-MP011095RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Igfbp1; Igfbp-1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    26-272
  • 氨基酸序列
    APQPW HCAPCTAERL ELCPPVPASC PEISRPAGCG CCPTCALPLG AACGVATARC AQGLSCRALP GEPRPLHALT RGQGACVLEP AAPATSSLSG SQHEEAKAAV ASEDELAESP EMTEEQLLDS FHLMAPSRED QPILWNAIST YSSMRAREIT DLKKWKEPCQ RELYKVLERL AAAQQKAGDE IYKFYLPNCN KNGFYHSKQC ETSLDGEAGL CWCVYPWSGK KIPGSLETRG DPNCHQYFNV QN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
  • 基因功能參考文獻：
    1. In simulated sleep apnea hypopnea syndrome, intermittent hypoxia in young rats does not cause physical growth retardation, but serum IGF-1 and IGFBP-3 levels decreased with the increase of hypoxia and decline of oxygen saturation. PMID: 22805023
    2. up-regulation of IGFBP-1 in oligodendrocytes in multiple sclerosis may serve two functions: (i) regulate IGF-1 actions, (ii) exert IGF-independent effects through its RGD sequence PMID: 20345750
    3. Insulin regulation of insulin-like growth factor-binding protein-1 gene expression PMID: 11784721
    4. regulation of expression by insulin is impaired by presence of hydrogen peroxide PMID: 11942857
    5. IGFBP-1 and IGFBP-3 are present in phosphorylated form in fasted rat skin, which induced inhibition of collagen biosynthesis in cultured fibroblasts PMID: 12670795
    6. IGFBP-1 released during the early steps of liver tissue damage and repair may interact with liver cells and potentiate the sensitivity of IGF-I to mitogenic signals. PMID: 15070850
    7. In this report we demonstrate that in H4IIE-C3 cells, four distinct classes of GSK-3 inhibitor mimic the effect of insulin on a third thymine-rich insulin response element-containing gene, IGFBP-1. PMID: 15350195
    8. Iron, radical oxygen species, and HIF-2 and -3 as well as prolyl hydroxylase pathways play important roles in mediating effects of hypoxia on IGFBP-1 gene expression in liver. PMID: 16166214
    9. insulin inhibition of IGFBP-1 mRNA levels can occur in the absence of the phosphorylation of Foxo1/Foxo3, whereas activation of the mTOR pathway is both necessary and sufficient PMID: 16455781
    10. Activation of the mTOR pathway, without activation of its upstream regulator PI 3-kinase, reduces IGFBP1 expression. PMID: 17032741
    11. Age-related oxidative stress underlies the upregulated JNK activation and IGFBP-1 expression. PMID: 17645865

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 數據庫鏈接：


主站蜘蛛池模板： 久久亚洲中文无码咪咪爱| 欧美亚洲国产一区二区三区| 特级av毛片免费观看| 亚洲国产精品特色大片观看完整版| 亚洲欧美国产成人综合欲网| 国内精品久久久久影视| 欧美国产亚洲日韩在线二区| 337p日本欧洲亚洲大胆精品| 国产午夜亚洲精品午夜鲁丝片| 成年女人18级毛片毛片免费| 18处破外女出血在线| 国产av成人无码精品网站| 亚洲成a人v欧美综合天堂| 人妻久久久一区二区三区| 天天狠天天透天干天干| 啪啪激情婷婷久久婷婷色五月| 日本xxxx少妇高清hd| 精品亚洲国产成人av| 人妻夜夜爽天天爽| 国产aⅴ精品一区二区三区久久| 蜜臀视频一区二区在线播放 | 久久偷看各类wc女厕嘘嘘| 无码国产精品一区二区免费式芒果| 熟睡中被义子侵犯在线播放| 亚洲精品国产一区二区图片| 久久久精品人妻一区二区三区蜜桃| 免费国精产品—品二品| 丁香婷婷激情综合俺也去| 国产高清视频色拍| 热re99久久精品国产99热| 日本乱人伦在线观看| 亚洲乱码日产一区三区| 西西人体www44rt大胆高清| 天天躁日日躁狠狠躁视频2021| 午夜精品久久久久久久99热| 欧美激情一区二区成人| 精品一区二区三区在线播放视频| 久久棈精品久久久久久噜噜 | 国产99视频精品免视看9| 蜜桃视频在线观看免费网址入口 | 中文字幕制服丝袜第57页|