在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs)

  • 中文名稱:
    大鼠Hgs重組蛋白
  • 貨號:
    CSB-YP010329RA
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Hgs重組蛋白
  • 貨號:
    CSB-EP010329RA
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Hgs重組蛋白
  • 貨號:
    CSB-EP010329RA-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Hgs重組蛋白
  • 貨號:
    CSB-BP010329RA
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Hgs重組蛋白
  • 貨號:
    CSB-MP010329RA
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Hgs; Hrs; Hrs2Hepatocyte growth factor-regulated tyrosine kinase substrate; SNAP-25-interacting protein Hrs-2
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-776
  • 氨基酸序列
    MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVNSIK KKVNDKNPHV ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQV EVNVRNKILY LIQAWAHAFR NEPKYKVVQD TYQIMKVEGH VFPEFKESDA MFAAERAPDW VDAEECHRCR VQFGVVTRKH HCRACGQIFC GKCSSKYSTI PKFGIEKEVR VCEPCYEQLN KKAEGKAAST TELPPEYLTS PLSQQSQLPP KRDETALQEE EELQLALALS QSEAEEKERM RQKSTYTAHP KSEPAPLASS APPAGSLYSS PVNSSAPLAE DIDPELARYL NRNYWEKKQE EARKSPTPSA PVPLTEPAAQ PGEGHTAPNS MVEAPLPETD SQPITSCSGP FSEQYQNGES EESHEQFLKA LQNAVSTFVN RMKSNHMRGR SITNDSAVLS LFQSINSTHP QLLELLNRLD ERRLYYEGLQ DKLAQIRDAR GALSALREEH REKLRRAAEE AERQRQIQLA QKLEIMRQKK QEYLEVQRQL AIQRLQEQEK ERQMRLEQQK QTVQMRAQMP AFPLPYAQLQ AMPTAGGVLY QPSGPTSFPG TFSPAGSVEG SPMHGVYMSQ PAPATGPYPS MPGTTADPSM VSAYMYPAGA PGAQAAPQAQ AGPTTNPAYS SYQPTPTPGY QNVASQAPQS LPAISQPPQT SNIGYMGSQP MSMGYQPYNM QNLMTTLPGQ DASLPAQQPY ITGQQPMYQQ MAPSTGPPQQ QPPVAQPPPT QGPPAQGNET QLISFD
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation. May contribute to the efficient recruitment of SMADs to the activin receptor complex.
  • 基因功能參考文獻(xiàn):
    1. Nedd4-2 induces binding of ENaC to Hrs, which mediates the sorting decision between ENaC degradation and recycling. PMID: 20675381
    2. Hrs and Tsg101 as crucial regulators of trafficking of Cx43 to lysosomes. PMID: 19808888
    3. Huntingtin-associated protein 1 interacts with this protein and functions in endosomal trafficking PMID: 12021262
    4. SNAP-25 is a receptor for Hrs on early endosomal membranes; the binding of Hrs to SNAP-25 on endosomal membranes inhibits formation of a SNARE complex required for homotypic endosome fusion. PMID: 12847087
    5. HRS can reduce the abundance of total and active EGFR and may reflect cell type-specific HRS function PMID: 16083858
    6. GRIF1 may participate in microtubule-based transport of early endosomes by acting as an adaptor linking Hrs-containing endosomes to kinesin. PMID: 17062640

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Endosome, multivesicular body membrane; Peripheral membrane protein.
  • 組織特異性:
    Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接:

    KEGG: rno:56084

    STRING: 10116.ENSRNOP00000051849

    UniGene: Rn.21



主站蜘蛛池模板: 国产福利一区二区三区在线视频| 亚洲高清最新av网站| 国产中文欧美日韩在线| 亚洲欧美日本韩国| 强开小婷嫩苞又嫩又紧韩国视频 | 国产xxxx99真实实拍| 高潮毛片无遮挡高清免费| 精品不卡一区二区| 高清精品一区二区三区| 欧美性色黄大片www喷水| 国产成人精品视觉盛宴| 日本xxxx18野外无毒不卡| 国产偷国产偷亚洲高清app| 国产一区二区三区久久精品| 久在线精品视频线观看| 亚洲精品成人福利网站| 少妇裸交aa大片| 精品国产乱码久久久久夜深人妻 | 99久久久无码国产精品性| 久久婷婷五月综合色首页| 久久亚洲精品无码观看不卡| 久久97久久97精品免视看| 成熟人妻av无码专区| 久久青青草原国产免费播放| 久久国产精品2020免费| 久久无码高潮喷水| 男ji大巴进入女人的视频| 一本一道av无码中文字幕| 国产9 9在线 | 免费| 熟女乱牛牛视频在线观看| 日本va在线视频播放| 夜夜未满十八勿进的爽爽影院| 久久久久蜜桃精品成人片| 人妻 偷拍 无码 中文字幕| 夜夜高潮夜夜爽夜夜爱爱一区| 无码日韩人妻精品久久蜜桃| 狠狠久久噜噜熟女| 另类亚洲小说图片综合区| 日本中文字幕亚洲乱码| 竹菊影视欧美日韩一区二区三区四区五区 | 久久aⅴ无码av高潮av喷吹 |