在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Guanine nucleotide-binding protein G (i) subunit alpha-2 (Gnai2)

  • 中文名稱:
    大鼠Gnai2重組蛋白
  • 貨號:
    CSB-YP009589RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Gnai2重組蛋白
  • 貨號:
    CSB-EP009589RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Gnai2重組蛋白
  • 貨號:
    CSB-EP009589RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Gnai2重組蛋白
  • 貨號:
    CSB-BP009589RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Gnai2重組蛋白
  • 貨號:
    CSB-MP009589RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Gnai2; Gnai-2Guanine nucleotide-binding protein G(i) subunit alpha-2; Adenylate cyclase-inhibiting G alpha protein
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-355
  • 氨基酸序列
    GCTVSAEDK AAAERSKMID KNLREDGEKA AREVKLLLLG AGESGKSTIV KQMKIIHEDG YSEEECRQYR AVVYSNTIQS IMAIVKAMGN LQIDFADPQR ADDARQLFAL SCAAEEQGML PEDLSGVIRR LWADHGVQAC FGRSREYQLN DSAAYYLNDL ERIAQSDYIP TQQDVLRTRV KTTGIVETHF TFKDLHFKMF DVGGQRSERK KWIHCFEGVT AIIFCVALSA YDLVLAEDEE MNRMHESMKL FDSICNNKWF TDTSIILFLN KKDLFEEKIT QSPLTICFPE YTGANKYDEA ASYIQSKFED LNKRKDTKEI YTHFTCATDT KNVQFVFDAV TDVIIKNNLK DCGLF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.
  • 基因功能參考文獻:
    1. paraventricular nucleus Galphai(2) protein pathways play an endogenous role in maintaining fluid and electrolyte balance by controlling the influence the sympathetic nervous system has on the renal handling of sodium PMID: 22459149
    2. endoplasmic reticulum-resident G(i2) protein is an important negative regulator of vesicular transport at the early stage of vesicle formation before coat protein assembly PMID: 21480366
    3. involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytes PMID: 11495629
    4. Gi2 has a role in regulating mitogenic activity in the neural progenitor cells of developing brain PMID: 15272018
    5. Alternatively spliced variant G alpha i2 is widely expressed in rat brain regions known to play a crucial role in brain function. PMID: 15312896
    6. heterologous desensitization in INS-1 cells may be mediated by Galphai2 changes but depend on the cAMP/PKA signalling pathway probably distant form the Galphai2 protein PMID: 15376236
    7. This novel alternatively spliced isoform of Galphai2 putatively encodes a truncated protein that could serve unique roles in the physiology of the vestibular neuroepithelium. PMID: 15950765
    8. Galphai2 has an essential regulatory role in ciliary function and cerebral spinal fluid homeostasis. PMID: 17430589
    9. results indicate that the upregulation of Gi2 in ischemic myocardium appears to be protective in inducing cell survival pathways to prevent myocyte death in response to ischemia/reperfusion injury PMID: 18316484
    10. Highest protein level was observed at the age of P0. There was also a trend of decline in the sGalphai2 protein from P0 to P90 in brain PMID: 18472243
    11. change of G[alpha]i2, G[alpha]q mRNA, and their proteins in severe acute pancreatitis PMID: 18665079
    12. role of Galpha(i2) in development of insulin resistance PMID: 18981538
    13. Overexpression of Galpha(i2), PDE2a, and RGS2 down-regulates the beta-adrenergic signaling pathway, thus contributing to the pathogenesis of cirrhotic cardiomyopathy. PMID: 19003918

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane; Lipid-anchor.
  • 蛋白家族:
    G-alpha family, G(i/o/t/z) subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 波多野结av衣东京热无码专区| 亚洲色欲综合一区二区三区| 国内女人喷潮完整视频| 69精品人人人人| 欧美丰满一区二区免费视频| 久久久精品欧美一区二区免费| 色资源av中文无码先锋| 2020国产欧洲精品网站| 中国精品无码免费专区午夜| 无码午夜人妻一区二区不卡视频| 国产手机在线无码播放视频 | 色在线 | 国产| 欧美老熟妇欲乱高清视频| 久久精品人妻一区二区蜜桃| 又色又污又爽又黄的网站| 色综合天天综合高清网国产在线| 国产欧美日韩亚洲精品专区| 999精品无码a片在线1级| 大白肥妇bbvbbw高潮| 国产情侣久久久久aⅴ免费| 亚洲第一网站男人都懂| 欧美黑人巨大videos精品男男| 国产欧美日韩亚洲18禁在线| 国产超碰人人模人人爽人人添| 一二三四在线观看免费视频| 色欲久久人妻内射| 国产精品无码久久综合网| 男人靠女人的免费视频| 无套内谢孕妇毛片免费看| 国内少妇偷人精品免费| 国产精品亚洲玖玖玖在线观看| 伊人99综合精品视频| 色狠狠成人综合网| 国产激情久久久久影院老熟女免费| 精品麻豆丝袜高跟鞋av| 国产l精品国产亚洲区| 精品av综合导航| 国产精品精华液网站| 欧美又大又粗午夜剧场免费| 男人的天堂免费一区二区视频| 人人添人人澡人人澡人人人人|