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  4. Recombinant Rat Endothelin-3 (Edn3)

Recombinant Rat Endothelin-3 (Edn3)

  • 中文名稱：
    大鼠Edn3重組蛋白
  • 貨號：
    CSB-YP007402RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Edn3重組蛋白
  • 貨號：
    CSB-EP007402RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Edn3重組蛋白
  • 貨號：
    CSB-EP007402RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Edn3重組蛋白
  • 貨號：
    CSB-BP007402RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Edn3重組蛋白
  • 貨號：
    CSB-MP007402RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Edn3
  • Uniprot No.：
  • 別名：
    Edn3Endothelin-3; ET-3; Preproendothelin-3; PPET3
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達區域：
    53-73
  • 氨基酸序列
    CTCFTYKD KECVYYCHLD IIW
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Endothelins are endothelium-derived vasoconstrictor peptides.
  • 基因功能參考文獻：
    1. A novel bidirectional interaction exists between endothelin-3 and retinoic acid in rat enteric nervous system precursors. PMID: 24040226
    2. ET-3-induced hemodynamic alterations are mediated by both ET-A and ET-B receptors PMID: 15093706
    3. The pronounced increase of endothelin-3 in the renal medulla is associated with preservation of local Nitric Oxide metabolite levels PMID: 15629454
    4. ET-3 effects on bile secretion are dependent on brain nitric oxide and independent of the autonomic nervous system or hemodynamic variations. PMID: 15949640
    5. Endothelin-3 diminished tyrosine hydroxylase activity in anterior hypothalamus and this effect was blocked by a selective ETB receptor antagonist (100 nM BQ-788), but not by a ET(A) receptor antagonist (BQ-610). PMID: 16023617
    6. Plays an important role in the growth control of colonic epithelial cells, possibly by mediating epithelial-mesenchymal interactions. PMID: 16287488
    7. Present results permit us to conclude that both endothelins play an important role in the regulation of norepinephrine neurotransmission at the presynaptic nerve endings in the hypothalamus. PMID: 18682267
    8. ET-3 significantly contributes to pulmonary vasoconstriction by activating the ET(B) at low concentration, and the ET(A) at high concentration. PMID: 18771698
    9. Present findings show a clear interaction between the endothelin system, and the catecholaminergic transmission in the olfactory bulb. PMID: 18850267

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Endothelin/sarafotoxin family
  • 數據庫鏈接：


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