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  4. Recombinant Rat E3 ubiquitin-protein ligase TRIM23 (Trim23)

Recombinant Rat E3 ubiquitin-protein ligase TRIM23 (Trim23)

  • 中文名稱：
    大鼠Trim23重組蛋白
  • 貨號：
    CSB-YP024459RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Trim23重組蛋白
  • 貨號：
    CSB-EP024459RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Trim23重組蛋白
  • 貨號：
    CSB-EP024459RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Trim23重組蛋白
  • 貨號：
    CSB-BP024459RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Trim23重組蛋白
  • 貨號：
    CSB-MP024459RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Trim23
  • Uniprot No.：
  • 別名：
    Trim23; Ard-1; Ard1; Arfd1; E3 ubiquitin-protein ligase TRIM23; EC 2.3.2.27; ADP-ribosylation factor domain-containing protein 1; GTP-binding protein ARD-1; RING-type E3 ubiquitin transferase TRIM23; Tripartite motif-containing protein 23
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-573
  • 氨基酸序列
    MAALAVNKPG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGHIGQY GAAEEALGIS GESIIRCDED EAHVASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCCQ HQVHAIEFVC LEEACQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCVRA YFSDLHETLC RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSQVSTACL HCKTLQQDDC RVVLAKQEIT RLLETLQKQQ QQFTEVADHI QLDASIPVTF TKDNRVYHGP KMEIRVVTLG LDGAGKTTIL FKLKQDEFMQ PIPTIGFNVE TVEYKNLKFT IWDVGGKHKL RPLWKHYYLN TQAVVFVVDS SHRDRISEAH SELAKLLTEK ELRDALLLIF ANKQDVAGAL SVEEITELLS LHKLCCGRSW YIQGCDARSG MGLYEGLDWL SRQLVAAGVL DVA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase 1/TBK1 by facilitating its dimerization and ability to phosphorylate the selective autophagy receptor SQSTM1. In order to achieve this function, TRIM23 mediates 'Lys-27'-linked auto-ubiquitination of its ADP-ribosylation factor (ARF) domain to induce its GTPase activity and its recruitment to autophagosomes.
  • 亞細胞定位：
    Cytoplasm. Endomembrane system. Golgi apparatus membrane. Lysosome membrane.
  • 蛋白家族：
    Small GTPase superfamily, Arf family
  • 數據庫鏈接：


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