在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat E3 SUMO-protein ligase PIAS2 (Pias2)

Recombinant Rat E3 SUMO-protein ligase PIAS2 (Pias2)

  • 中文名稱：
    大鼠Pias2重組蛋白
  • 貨號：
    CSB-YP728126RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Pias2重組蛋白
  • 貨號：
    CSB-EP728126RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Pias2重組蛋白
  • 貨號：
    CSB-EP728126RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Pias2重組蛋白
  • 貨號：
    CSB-BP728126RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Pias2重組蛋白
  • 貨號：
    CSB-MP728126RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Pias2; Miz1; Piasx; E3 SUMO-protein ligase PIAS2; EC 2.3.2.-; Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; E3 SUMO-protein transferase PIAS2; Msx-interacting-zinc finger protein; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-572
  • 氨基酸序列
    MADFEELRNM VSSFRVSELQ VLLGFAGRNK SGRKHDLLMR ALHLLKSGCT PAVQIKIREL YRRRYPRTLE GLSDLSTIKS SVFSLDGSSS PVEPDLAVAG IHSLPSTSIA PHSPSSPVAS VLLQDTKPTF EMQQPSPPIP PVHPDVQLKT LPFYDVLDVL IKPTSLVQSS IQRFQEKFFI FALTPQQVRE ICISRDFLPG GRRDYTVQVQ LRLCLAETSC PQEDNYPNSL CIKVNGKLFP LPGYAPPPKN GIEQKRPGRP LNITSLVRLS SAVPNQISIS WASEIGKNYS MSVYLVRQLT SAMLLQRLKM KGIRNPDHSR ALIKEKLTAD PDSEIATTSL RVSLMCPLGK MRLTIPCRAV TCTHLQCFDA ALYLQMNEKK PTWICPVCDK KAAYESLILD GLFMEILNDC SDVDEIKFQE DGSWCPMRPK KEAMKVTSQP CTKVESSSVF SKPCSVTVAS DASKKKIDVI DLTIESSSDE EEDPPAKRKC IFMSETQSSP TKGVLMYQPS SVRVPSVTSV DPAAIPPSLT DYSVPFHHTP VSSMSSDLPG EQRRNDINNE VQLGTSSDTV QQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and PIAS2 isoform studied. However, it seems to be mostly involved in gene silencing. Binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity. Sumoylates PML at'Lys-65' and 'Lys-160'.
  • 基因功能參考文獻：
    1. functions for ZBTB17 in the heart, a transcription factor that may play a role as a novel cardiomyopathy gene PMID: 26175529
    2. Decreasing MIZ1 expression was closely correlated with inflammatory response, and development of acute necrotizing pancreatitis. PMID: 26581215
    3. Miz-1 is essential for Myc-mediated apoptosis PMID: 16352593
  • 亞細胞定位：
    Nucleus speckle. Nucleus, PML body. Nucleus.
  • 蛋白家族：
    PIAS family
  • 組織特異性：
    Mainly expressed in testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产亚洲精品久久久久久国| 欧美激情在线播放| 夜夜爽夜夜叫夜夜高潮漏水| 热99re久久精品天堂| 国产av国片精品有毛| 亚洲精品久久久久中文字幕| 女人和拘做爰正片视频| 久天啪天天久久99久久| 中国性欧美videofree精品| 日本成熟少妇喷浆视频| 人妻av综合天堂一区| 欧美激情第1页| 18禁无遮挡无码网站免费| 国产偷国产偷亚洲清高孕妇| 777午夜精品免费观看| 精品人妻系列无码人妻漫画| 国产极品美女高潮抽搐免费网站| 中国人妻被两个老外三p| 欧美xxxx做受欧美人妖| 欧美颜射内射中出口爆在线| 在线人人车操人人看视频| 国产午精品午夜福利757视频播放| 国产精品偷伦视频观看免费| 天堂在线最新版资源www中文| 国产69久久精品成人看| 日本熟妇色一本在线视频| 鲁死你av资源站| 久久久性色精品国产免费观看| 亚洲精品无码av中文字幕电影网站| 日本日本熟妇中文在线视频| 亚洲多毛妓女毛茸茸的| 无码人妻丰满熟妇区毛片| 国产区精品一区二区不卡中文| 国产一区二区三区在线观看免费| 天天做天天爱天天爽综合网| 国产在线无码不卡影视影院| 欧美一区二区三区久久综| 精品无码国产一区二区三区51安| 国产午夜鲁丝无码拍拍| 久久久久久亚洲精品a片成人| 一二三四在线视频社区3|