在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Double-stranded RNA-specific editase 1 (Adarb1)

Recombinant Rat Double-stranded RNA-specific editase 1 (Adarb1)

  • 中文名稱：
    Recombinant Rat Double-stranded RNA-specific editase 1(Adarb1)
  • 貨號(hào)：
    CSB-YP001325RA
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Double-stranded RNA-specific editase 1(Adarb1)
  • 貨號(hào)：
    CSB-EP001325RA
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Double-stranded RNA-specific editase 1(Adarb1)
  • 貨號(hào)：
    CSB-EP001325RA-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Double-stranded RNA-specific editase 1(Adarb1)
  • 貨號(hào)：
    CSB-BP001325RA
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Double-stranded RNA-specific editase 1(Adarb1)
  • 貨號(hào)：
    CSB-MP001325RA
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Adarb1
  • Uniprot No.：
  • 別名：
    Adarb1; Red1; Double-stranded RNA-specific editase 1; EC 3.5.4.37; RNA-editing deaminase 1; RNA-editing enzyme 1; dsRNA adenosine deaminase
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-711
  • 氨基酸序列
    MDIEDEENMS SSSIDVKENR NLDNMPPKDS STPGPGEGIP LSNGGGGSTS RKRPLEEGSN GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYMLLSQ TGPVHAPLFV MSVEVNGQVF EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF ETPDKSEPPF YVGSNGDDSF SSSGDVSLSA SPVPASLTQP PLPIPPPFPP PSGKNPVMIL NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALATVFNLH LDQTPSRQPV LSEGLQLHLP QVLADAVSRL VLGKFSDLTD NFSSPHARRK VLSGVVMTTG TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYAQ LELYLNNKED QKKSIFQKSE RGGFRLKDTV QFHLYISTSP CGDARIFSPH EPVLEGMAPD SHQLTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ TWDGVLQGER LLTMSCSDKI ARWNVVGIQG ALLSIFVEPI YFSSIILGSL YHGDHLSRAM YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDTAIE VINATTGKDE LGRPSRLCKH ALYCRWMRVH GKVPPHLLRT KITKPTTYHE SKLAAKEYQA AKARLFTAFI KAGLGAWVEK PTEQDQFSFT P
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing). Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alter their functional activities. Edits GRIA2 at both the Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently. Can inhibit cell proliferation and migration and can stimulate exocytosis.
  • 基因功能參考文獻(xiàn)：
    1. lower levels of ADAR2 in the nucleus of immature neurons than in mature neurons. PMID: 28082424
    2. The JNK1 pathway may be functionally linked to the nutrient-sensing actions of ADAR2-mediated RNA editing in professional secretory cells. PMID: 23139803
    3. Cleaved ADAR2 leads to a decrease or loss of GluR2 editing, which will further result in high Ca2 influx and excitotoxic neuronal death. PMID: 21620933
    4. interaction with RNA transcripts containing selective and nonselective editing sites PMID: 12810917
    5. the nucleolar localization of ADAR2 represents an important mechanism by which RNA editing can be modulated by the sequestration of enzymatic activity from potential RNA substrates in the nucleoplasm PMID: 14612560
    6. both sequence and structural elements are required to define adenosine moieties targeted for specific ADAR2-mediated deamination PMID: 14660658
    7. results implicate the carboxy-terminal domain of the large subunit of RNA polymerase II in site-selective RNA editing by ADAR2 and in coordination of editing with alternative splicing. PMID: 16440002
    8. RNA structure-dependent recognition by the two double-stranded RNA binding motifs of rat ADAR2. PMID: 16472753
    9. ADAR2 double-stranded RNA binding motifs serve differential roles in RNA dimerization in RNA eduting. PMID: 16682559
    10. RNA editing by ADAR2 in pancreatic islets and beta-cells is metabolically regulated by nutritional and energy status PMID: 16956888

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Nucleus, nucleolus.
  • 組織特異性：
    Brain and peripheral tissues.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 精品国产免费第一区二区三区| 日韩熟女精品一区二区三区| 中文字幕无码中文字幕有码| 中文字幕亚洲制服在线看| 4hu四虎永久在线影院| 大胸少妇午夜三级| 一女被多男玩喷潮视频| 丰满岳乱妇在线观看中字 | 色播在线精品一区二区三区四区| 国产女人高潮抽搐喷水视频| 人妻少妇精品无码专区动漫| 久久久无码人妻精品无码| 女m羞辱调教视频网站| 久久精品亚洲中文字幕无码麻豆| 人妻 色综合网站| 又色又爽又高潮免费视频国产| 国产综合视频一区二区三区| 人妻少妇乱子伦精品无码专区电影| 日本中文字幕有码在线视频| 在线 无码 中文字幕 强 乱| 曰韩a∨无码一区二区三区| 老色鬼永久精品网站| 国产精品永久免费视频| 午夜精品久久久久久久四虎| 久久天天躁狠狠躁夜夜2019| 99久久婷婷国产综合精品青草免费| 亚洲精品乱码久久久久久蜜桃不卡| 西西艺术人像摄影| 蜜臀av性久久久久蜜臀aⅴ | 少妇爆乳无码专区| 成人精品视频一区二区三区尤物| 国产高清视频在线观看69| 国产亚洲综合区成人国产系列| 内射无码专区久久亚洲| 国产成人综合95精品视频| 亚洲精品aa片在线观看国产| 亚洲性啪啪无码av天堂| 亚洲综合激情另类小说区| 污污网站18禁在线永久免费观看| 无卡无码无免费毛片| 亚洲国产精品久久久久久|