在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Double-stranded RNA-binding protein Staufen homolog 2 (Stau2)

Recombinant Rat Double-stranded RNA-binding protein Staufen homolog 2 (Stau2)

  • 中文名稱：
    大鼠Stau2重組蛋白
  • 貨號：
    CSB-YP721243RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Stau2重組蛋白
  • 貨號：
    CSB-EP721243RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Stau2重組蛋白
  • 貨號：
    CSB-EP721243RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Stau2重組蛋白
  • 貨號：
    CSB-BP721243RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Stau2重組蛋白
  • 貨號：
    CSB-MP721243RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Stau2
  • Uniprot No.：
  • 別名：
    Stau2; Double-stranded RNA-binding protein Staufen homolog 2; r-staufen protein
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-571
  • 氨基酸序列
    MANPKEKTPM CLVNELARFH SIQPQYKLLN ESGPAHSKMF SVQLSLGEQT WESEGSSIKK AQQAVANKAL TESTLPKPVQ KPPKSNVNNN PGSITPTVEL NGLAMKRGEP AIYRPLDPKP FPNYRANYNF RGMYNQRYHC PMPKIFYVQL TVGNNEFFGE GKTRQAARHN AAMKALQALQ NEPIPEKSPQ NGESGKEMDD DKDANKSEIS LVFEIALKRN MPVSFEVIKE SGPPHMKSFV TRVSVGEFSA EGEGNSKKLS KKRAATTVLQ ELKKLPPLPV IEKPKLFFKK RPKTIIKAGP EYGQGMNPIS RLAQIQQARK EKEPDYVLLS ERGMPRRREF VMQVKVGNEV ATGTGPNKKI AKKNAAEAML LQLGYKASTS LQDQLDKTGE NKGWSGPKPG FPEPANNTPK GILHLSPDVY QEMEASRHRV TSGTTLGYLS PKDMNQPSSS FFSVESPSPT SSAPAARELL MNGTSPAAEA IGLKGSSPTP PCSSVQPSKQ LEYLARIQGF QAALSALKQF SEQGLESIDG VVNVENGSLE KQAKHLREKA DNNQANPGSI TQDCKKSKSV I
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body.
  • 基因功能參考文獻：
    1. RBP Stau2 plays an important role in the regulation of specific aspects of hippocampal synaptic plasticity and learning and memory. PMID: 29149906
    2. results identify the retained intron as a critical element in recruiting Stau2, which then allows for the localization of Calm3L mRNA to distal dendrites PMID: 28765142
    3. Here, we describe a new role for the ATP-dependent helicase UPF1 and its interaction with the RNA localization protein STAU2 in mediating mGluR-LTD through the regulation of mRNA translation complexes stalled at the level of elongation and/or termination. PMID: 28821679
    4. Stau2 stabilizes expression of Rgs4 mRNA via its 3' UTR in hippocampal neurons. PMID: 24360961
    5. Stau2 isoforms expressed in the developing eye of chicken embryo prevent microphthalmia. PMID: 22940085
    6. Recruitment of Stau2 alone or in combination with Upf1 differentially affects the fate of mRNAs. PMID: 22087843
    7. These results represent an additional and important step in the characterization of Staufen2- mediated neuronal functions in rat brains. PMID: 20510018
    8. provide new tools to study and understand how Stau2-containing mRNPs are transported, translationally silenced during transport and/or locally expressed according to cell needs PMID: 20596529
    9. Data show that an isoform of Staufen2, Stau2(59), is exported from the nucleus by two distinct pathways, one of which is RNA-binding domain 3-mediated and the other of which is CRM1 (exportin 1)-dependent. PMID: 15364930
    10. A pool of Staufen2 is present in neuronal nuclei and colocalizes to a large degree with p62 and partly with Tap, Y14, and Mago. PMID: 15970630
    11. Data suggest an important role for Staufen2 in the formation and maintenance of dendritic spines of hippocampal neurons. PMID: 16418534
    12. Overall, these results suggest that dendritic mRNA transport is mediated via the Staufen2 and kinesin motor proteins and might be modulated by the neuronal activity and mitogen-activated protein kinase pathway. PMID: 17587311
    13. These results suggest that the MAPK pathway could modulate dendritic mRNA transport through its interaction with Staufen2. PMID: 18492489

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus, nucleolus. Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Shuttles between the nucleolus, nucleus and the cytoplasm. Nuclear export of isoform 1 is independent of XPO1/CRM1 and may require the exportin XPO5. Nuclear export of isoform 2 and isoform 3 can occur by both XPO1/CRM1-dependent and XPO1/CRM1-independent pathways. Found in large cytoplasmic ribonucleoprotein (RNP) granules which are present in the actin rich regions of myelinating processes and associated with microtubules, polysomes and the endoplasmic reticulum. Also recruited to stress granules (SGs) upon inhibition of translation or oxidative stress. These structures are thought to harbor housekeeping mRNAs when translation is aborted.
  • 組織特異性：
    Expressed in both somata and dendrites of hippocampal neurons.
  • 數據庫鏈接：


主站蜘蛛池模板： 中国熟女仑乱hd| 69成人免费视频无码专区| 国产精品久久久久9999不卡| 99久re热视频这里只有精品6| 两口子交换真实刺激高潮| 亚洲色欲久久久久综合网| 日本少妇高潮喷水免费可以看| 一区二区三区国产精华液| 无套中出丰满人妻无码| 国产精品无码一区二区在线| av无码人妻无码男人的天堂| 深夜爽爽动态图无遮无挡| 性一交一乱一伦一色一情孩交| 女人被狂躁60分钟视频| 欧美人成视频在线视频| 中文无码人妻影音先锋| 国产精品.xx视频.xxtv| 久久亚洲精品无码网站| 久久国产欧美成人av| 国产麻豆剧果冻传媒白晶晶| 一卡二卡三卡视频| 天天爽夜夜爽人人爽从早干到睌| 99久热国产精品视频尤物| 麻豆传传媒久久久爱| 乱人伦中文视频在线| 国产成人一区二区无码不卡在线| 377p欧洲日本亚洲大胆| 起碰免费公开97在线视频| 成视频年人黄网站视频福利| 成人网站www污污污网站 | 亚洲国产成人va在线观看天堂| 性xxx欧美老妇5060.70| 久青青视频在线观看久| 成人毛片一区二区| 成人精品视频在线观看不卡| 欧美三级在线播放线观看| 成人无码一区二区三区| 免费精品国偷自产在线在线| 国产精品亚洲一区二区z| 亚洲色婷婷一区二区三区| 成在人线av无码免费高潮水老板|