在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat DNA damage-binding protein 1 (Ddb1), partial

Recombinant Rat DNA damage-binding protein 1 (Ddb1), partial

  • 中文名稱：
    Recombinant Rat DNA damage-binding protein 1(Ddb1) ,partial
  • 貨號：
    CSB-YP884161RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat DNA damage-binding protein 1(Ddb1) ,partial
  • 貨號：
    CSB-EP884161RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat DNA damage-binding protein 1(Ddb1) ,partial
  • 貨號：
    CSB-EP884161RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat DNA damage-binding protein 1(Ddb1) ,partial
  • 貨號：
    CSB-BP884161RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat DNA damage-binding protein 1(Ddb1) ,partial
  • 貨號：
    CSB-MP884161RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ddb1DNA damage-binding protein 1; Damage-specific DNA-binding protein 1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. DCX(DDB2) (also known as DDB1-CUL4-ROC1, CUL4-DDB-ROC1 and CUL4-DDB-RBX1) may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. DCX(DDB2) also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. DCX(ERCC8) (the CSA complex) plays a role in transcription-coupled repair (TCR). The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1. DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DDB1 family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 高大丰满欧美熟妇hd| 自拍偷在线精品自拍偷免费| 国产亚洲精aa在线观看| 国产内射爽爽大片| 6080yyy午夜理论片中无码| 人妻无码一区二区不卡无码av| 亚洲综合色在线视频www| 亚洲区小说区激情区图片区| 久久国产亚洲精品无码| 国产精品成人无码免费| 日本护士╳╳╳hd少妇| 国产日韩欧美久久久精品图片| 国产成人av在线播放影院| 亚洲精品久久久一区| 中文字幕精品久久久久人妻红杏1 久久久精品日本一区二区三区 | 国产精品99久久久久久www| 激情综合激情五月俺也去| 日韩高清在线亚洲专区小说| 日本xxx在线观看免费播放| 少妇av射精精品蜜桃专区| 摸丰满大乳奶水www免费| 好了av四色综合无码久久| 在线看片免费人成视频国产片| 国产顶级熟妇高潮xxxxx| 午夜阳光精品一区二区三区| 久久先锋男人av资源网站| 日韩av爽爽爽久久久久久| 国产老熟女狂叫对白| 男女后式激烈动态图片| 国产一区二区精品久久岳| 奇米在线7777在线精品| 亚洲伊人成综合网2222| 真人与拘做受免费视频| 亚洲精品国产成人一区二区| 亚洲伊人色欲综合网无码中文| 亚洲中文字幕一区精品自拍| yy111111少妇无码理论片| 国产爆乳无码av在线播放| 久久精品国产成人午夜福利| 日日噜噜噜噜夜夜爽亚洲精品| 欧美丰满一区二区免费视频|