在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2 (Cdkn2a)

  • 中文名稱:
    Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2(Cdkn2a)
  • 貨號:
    CSB-YP848084RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2(Cdkn2a)
  • 貨號:
    CSB-EP848084RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2(Cdkn2a)
  • 貨號:
    CSB-EP848084RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2(Cdkn2a)
  • 貨號:
    CSB-BP848084RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rat Cyclin-dependent kinase inhibitor 2A, isoform 2(Cdkn2a)
  • 貨號:
    CSB-MP848084RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cdkn2a; Tumor suppressor ARF; Alternative reading frame; ARF; Cyclin-dependent kinase inhibitor 2A; p19ARF
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-160
  • 氨基酸序列
    MGRRFVVTVR IRRTGRSPQV RVFLVQFLGS SRPRSANGTR GFVALVLRPE RIARRGPQPH PGPGDDDGQR QSGSSPALLW CRFELRGPHH PLPTGARRSA GGLPRHSGST APGRGAAGCA RCLGSPAARP GPRAGTSRRR AVFAVSTLLR WERFPGHRQA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with COMMD1 and promotes its 'Lys63'-linked polyubiquitination. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
  • 亞細胞定位:
    Nucleus, nucleolus. Nucleus, nucleoplasm.
  • 組織特異性:
    Widely expressed with very low levels in kidney and colon.
  • 數據庫鏈接:

    UniGene: Rn.48717



主站蜘蛛池模板: 超清无码av最大网站| 抽插丰满内射高潮视频| 国产精品美女久久久久久| 老子午夜理论影院理论| 东北老女人高潮大喊舒服死了 | 国产热re99久久6国产精品首页| 丰满人妻一区二区三区视频53| 夜夜躁狠狠躁日日躁孕妇| aaa欧美色吧激情视频| 加勒比东京热无码一区| 美女裸体视频永久免费| 无码国模国产在线观看免费| 人妻少妇精品视中文字幕国语| 7777奇米四色成人眼影| 精品夜夜澡人妻无码av蜜桃| 国产高潮抽搐喷水高清| 忘忧草社区在线资源www| 中文乱码免费一区二区三区| 色狠狠成人综合网| 欧美黑人粗大xxxxbbbb| 中文字日产乱码免费1~3软件 | 国产92成人精品视频免费| 久久人人爽人人爽人人片dvd| 97人妻免费碰视频碰免 | 国产精品成人一区二区三区 | 久久久久影院美女国产主播| 撕开奶罩揉吮奶头视频| 欧美v亚洲v日韩v最新在线| 久久无码中文字幕无码| 亚洲精品成人网站在线| 亚洲中文字幕无码中文字在线 | 国产久热精品无码激情| 亚洲龙腾成小说人网| 亚洲精品色情app在线下载观看| 99热精品久久只有精品| 久久男人av资源站| 免费视频好湿好紧好大好爽| 公么大龟弄得我好舒服秀婷视频| 伊人色综合久久天天小片| 国内精品国语自产拍在线观看| 精品国产天堂综合一区在线|