在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5 (Atf5)

Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5 (Atf5)

  • 中文名稱：
    Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5(Atf5)
  • 貨號：
    CSB-YP750819RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5(Atf5)
  • 貨號：
    CSB-EP750819RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5(Atf5)
  • 貨號：
    CSB-EP750819RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5(Atf5)
  • 貨號：
    CSB-BP750819RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Cyclic AMP-dependent transcription factor ATF-5(Atf5)
  • 貨號：
    CSB-MP750819RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Atf5
  • Uniprot No.：
  • 別名：
    Atf5; AtfxCyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-281
  • 氨基酸序列
    MSLLATLGLE LDRALLPASG LGWLVDYGKL PLAPAPLGPY EVLGGALEGG LPGGGEPLAG DGFSDWMTER VDFTALLPLE APLPPGTLPP PSPAPPDLEA MASLLKKELE QMEDFFLDAP LLPPPSPPPP PPPAPSLPLP LPLPTFDLPQ PPTLDTLDLL AVYCRSEAGP GDSGLTTLPV PQQPPPLAPL PSLSRPAPYP SPASTRGDRK QKKRDQNKSA ALRYRQRKRA EGEALEGECQ GLEARNRELR ERAESVEREI QYVKDLLIEV YKARSQRTRS A
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate. Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation. Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes. May be involved in osteogenic differentiation. Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1. Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1. Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent. Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver. In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase. May act as a negative regulator of IL1B transduction pathway in liver. Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members. Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation. Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner. Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material.
  • 基因功能參考文獻：
    1. an essential role for HSP70 in maintaining high levels of ATF5 expression in glioma cells and support the conclusion that ATF5 is an important substrate protein of HSP70 that mediates HSP70-promoted cell survival in glioma cells. PMID: 21521685
    2. ATF5 blocks the differentiation of neuroprogenitor cells into neurons and must be downregulated to permit this process to occur. PMID: 12805299
    3. Results indicat that ATF5 promoted H9c2 cell survival in heat shock stress at least through activation of Hsp27. PMID: 17606386
    4. Results show that serum shock of PC12 cells triggered circadian expression of Atf5. PMID: 17823250
    5. Identified a novel ATF5 consensus DNA binding sequence. Demonstrate in C6 glioma and MCF-7 breast cancer cells that ATF5 occupies this sequence and that ATF5 activates reporter gene expression driven by this site. PMID: 19531563

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族：
    BZIP family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲在av极品无码天堂手机版| 国产亚洲精品字幕在线观看| 激情内射日本一区二区三区| 日本高清视频色wwwwww色| 亚洲国产成人久久久网站| 人妻三级日本三级日本三级极| 农村欧美丰满熟妇xxxx| 国产激情无码一区二区三区| 日本妇人成熟免费视频| 国产成人a无码短视频| 凹凸在线无码免费视频| 日韩免费无码一区二区视频| 国产精品国产三级国产an | 国产日产欧美最新| 亚洲国产一区二区三区波多野结衣| 柠檬福利精品视频导航| 被c到高潮疯狂喷水国产| 国产初高中生真实在线视频| 亚洲精品自在在线观看| 最新系列国产专区|亚洲国产| 国产l精品国产亚洲区| 成年午夜无码av片在线观看| 欧美叉叉叉bbb网站| 亚洲欲色欲色xxxxx在线观看 | 国产精品女主播主要上线| 好想被狂躁无码视频在线观看| 久久久精品午夜免费不卡| 女同性av片在线观看免费网站| 激情综合五月丁香亚洲| 精品无码专区毛片| 女人的精水喷出来视频| 全部露出来毛走秀福利视频| 朋友的丰满人妻中文字幕| 国产精品av免费观看| 白丝乳交内射一二三区| 中文字幕日本乱码仑区在线| 一本一道久久综合狠狠老| 国产精品卡1卡2卡三卡四| 午夜爱爱爱爱爽爽爽网站| 四虎国产精品免费久久久| 国产一区二区三区乱码|