Recombinant Rat Chondroitin sulfate proteoglycan 5 (Cspg5), partial

^{In Stock}

中文名稱：

Recombinant Rat Chondroitin sulfate proteoglycan 5 (Cspg5), partial
貨號：

CSB-EP866833RA
規格：

￥1536
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

Cspg5
Uniprot No.：

Q9ERQ6
別名：

Acidic leucine-rich EGF-like domain-containing brain protein;Neuroglycan C
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
來源：

E.coli
分子量：

47.3 kDa
表達區域：

31-428aa
氨基酸序列

VPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged and C-terminal Myc-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
基因功能參考文獻：
1. Rac1, Cdc42, and RhoG perform very specific and non-redundant functions at different levels of hierarchy in regulating dendritic tree complexity induced by CALEB/NGC PMID: 27412363
2. there is a glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C PMID: 15331613
3. neuroglycan C is a novel component of midkine receptors involved in process elongation PMID: 16901907
4. PI3K-Akt-mammalian target of rapamycin (mTOR) signaling pathway and PKC are important for CALEB/NGC-induced stimulation of dendritic branching. CALEB/NGC-induced spine morphogenesis is independent of PI3K but depends on PKC. PMID: 17431398
亞細胞定位：

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, synaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cell surface.
組織特異性：

Expressed in cerebral cortex and cerebellum. Expressed in retina (at protein level).
數據庫鏈接：

KEGG: rno:50568

STRING: 10116.ENSRNOP00000028278

UniGene: Rn.10146