在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Calcium calmodulin-dependent 3,5 cyclic nucleotide phosphodiesterase 1C (Pde1c)

Recombinant Rat Calcium calmodulin-dependent 3,5 cyclic nucleotide phosphodiesterase 1C (Pde1c)

In Stock
  • 中文名稱：
    大鼠Pde1c重組蛋白
  • 貨號：
    CSB-EP720512RA
  • 規(guī)格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cam-PDE 1C;3',5'-cyclic-AMP phosphodiesterase (EC:3.1.4.-By similarity);3',5'-cyclic-GMP phosphodiesterase
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    92.6 kDa
  • 表達區(qū)域：
    1-768aa
  • 氨基酸序列
    MTDTSHKKEGFKKCRSATFSIDGYSFTIVANEAGDKNARPLARFSRSKSQNCLWNSLIDGLTGNVKEKPRPTIVQDTRPPEEILADELPQLDSPEALVKTSFRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSINSSDAKRSGVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVQINRERWRAKVPKEEKAKKEAEEKARLAAEEKQKEMEAKSQAEQGTTSKAEKKTSGETKGQVNGTRTSKGDNPRGKNSKGDKAGEKQQNGDLKDGKNKADKKDHSNTGNESKKADGTKKRSHGSPAPSTSSTSRLTLPVIKPPLRHFKRPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKIKKIQNISHHWNKK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal?6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

引用文獻

產(chǎn)品評價

靶點詳情

  • 功能：
    Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB.
  • 基因功能參考文獻：
    1. In cultured rat aortic SMCs, PDE1C deficiency or PDE1 inhibition attenuated SMC proliferation and migration. PDE1C plays a critical role in regulating the stability of growth factor receptors, endocytosis and lysosome-dependent degradation. PMID: 25608528
    2. Suggest that PDE1C plays a critical role in regulating collagen homeostasis during pathological vascular remodeling. PMID: 21148428
  • 蛋白家族：
    Cyclic nucleotide phosphodiesterase family, PDE1 subfamily
  • 組織特異性：
    Highly expressed in olfactory epithelium and at moderate levels, in cerebellum, as well as weakly in forebrain, testis, heart and lung. In the olfactory epithelium, expressed by sensory neurons, but not epithelial cells.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 夜色爽爽影院18禁妓女影院| 国产精品亚洲精品日韩已满十八小 | 男人和女人在床的app| 国产精品沙发午睡系列990531| 狠狠综合亚洲综合亚洲色| 国产欧色美视频综合二区| 小13箩利洗澡无码视频网站| 国产女人18毛片水真多1| 无码精品人妻一区二区三区人妻斩| 色欲人妻aaaaaa无码| 2021国产成人精品久久| 日日摸日日碰人妻无码老牲| 亚洲人成网站观看在线播放| 欧美激情精品成人一区| 久久精品第九区免费观看| 国产a在亚洲线播放| 久久久国产成人一区二区| 中文字幕av伊人av无码av狼人| 女厕厕露p撒尿八个少妇| 久久久久久综合网天天| 国产男生午夜福利免费网站| 国产精品无码一区二区牛牛| 狠狠综合久久综合88亚洲| 成年女人18级毛片毛片免费| 久久五十路丰满熟女中出| 中文字幕人妻第一区| 67194熟妇在线观看线路| 国产熟妇勾子乱视频| 国产人成高清在线视频99最全资源| 伊人色合天天久久综合网| 亚洲色欲色欲大片www无码| 99国产精品白浆在线观看免费| 成人午夜高潮刺激免费视频| 国产真实露脸乱子伦| 日本三级吃奶头添泬无码苍井空 | 精品熟女少妇av免费久久| 精品黑人一区二区三区| 成人av久久一区二区三区| 午夜不卡无码中文字幕影院| 午夜射精日本三级| 欧美亚洲日本国产综合在线|