在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat ADP-ribosylation factor 1 (Arf1)

  • 中文名稱:
    Recombinant Rat ADP-ribosylation factor 1(Arf1)
  • 貨號:
    CSB-YP001988RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rat ADP-ribosylation factor 1(Arf1)
  • 貨號:
    CSB-EP001988RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Rat ADP-ribosylation factor 1(Arf1)
  • 貨號:
    CSB-EP001988RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rat ADP-ribosylation factor 1(Arf1)
  • 貨號:
    CSB-BP001988RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rat ADP-ribosylation factor 1(Arf1)
  • 貨號:
    CSB-MP001988RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Arf1ADP-ribosylation factor 1
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-181
  • 氨基酸序列
    GNIFANLFK GLFGKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKLGLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
  • 基因功能參考文獻:
    1. Arf1 is a critical regulator of actin dynamics and synaptic function via modulation of PICK1. PMID: 23889934
    2. ARF1-dependent trafficking of procathepsin B and the maturation of autophagosomes results in cathepsin B-mediated trypsinogen activation induced by caerulein. PMID: 22570480
    3. Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism PMID: 21187408
    4. Activation of a non-voltage-activated Na(+)-selective current requires Arf1. PMID: 14563210
    5. Arf GTPases are expressed and targeted in a cell- and membrane-specific pattern in kidney epithelial cells in situ. PMID: 14684384
    6. an Arf1-GBF1-Brefeldin A complex is formed and has a longer residence time on Golgi membranes than GBF1 or Arf1 alone PMID: 15616190
    7. Overexpression of ARF1 increased the assembly of VLDL 2 but not of VLDL 1, whose production was dependent on both anterograde transport and the availability of fatty acids. PMID: 15618550
    8. ARF1 and ARF6 are both found on peroxisomes, but coatomer recruitment only depends on ARF1-GTP PMID: 16100119
    9. The role of Arf1 in polarization of the Golgi apparatus is established. PMID: 16101683
    10. ARF1 is active during mitosis and this activity is required for mitotic Golgi fragmentation. PMID: 17562717
    11. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410
    12. Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding. PMID: 18693248

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus. Cytoplasm, perinuclear region. Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density. Membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor.
  • 蛋白家族:
    Small GTPase superfamily, Arf family
  • 數據庫鏈接:


主站蜘蛛池模板: 久久九九精品国产免费看小说| 十八禁视频网站在线观看| 免费人成年激情视频在线观看| 国产人妻高清国产拍精品| 亚洲国产精品成人精品无码区蜜臀| 亚洲人成黄网站69影院| 国产精品久久久久久久久久久免费看 | 亚洲欧美精品aaaaaa片| 亚洲人成电影网站色| 色综合天天天天综合狠狠爱| 色琪琪av中文字幕一区二区| 午夜日本大胆裸艺术| 57pao成人国产永久免费视频| 午夜福利在线永久视频| 国产婷婷精品av在线| 日韩不卡1卡2卡三卡2021免费 | 亚洲国产成人精品无码区在线观看 | 无码熟熟妇丰满人妻啪啪| 激情97综合亚洲色婷婷五| 天天摸夜夜添狠狠添婷婷| 人妻丰满av无码久久不卡| 亚洲国产成人久久综合三区| 极品国产主播粉嫩在线| 99精品免视看| 蜜臀av无码人妻精品| 国产乱妇乱子在线播放视频| 久久精品国产999久久久| 肉色丝袜足j视频国产| 手机福利视频| 热久久美女精品天天吊色| 日韩国产精品无码一区二区三区| 中国丰满熟妇av| 50岁熟妇大白屁股真爽| 国产乱人对白| 欧美大片18禁aaa免费视频| 2021精品亚洲中文字幕| 国产凹凸在线一区二区| 北条麻妃一区二区三区av高清| 久久久青草青草免费看| 亚洲欧洲日本综合aⅴ在线 | 免费视频成人片在线观看|