在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Srd5a1), partial

Recombinant Rat 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Srd5a1), partial

  • 中文名稱：
    大鼠Srd5a1重組蛋白
  • 貨號：
    CSB-YP022653RA1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Srd5a1重組蛋白
  • 貨號：
    CSB-EP022653RA1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Srd5a1重組蛋白
  • 貨號：
    CSB-EP022653RA1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Srd5a1重組蛋白
  • 貨號：
    CSB-BP022653RA1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Srd5a1重組蛋白
  • 貨號：
    CSB-MP022653RA1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Srd5a1
  • Uniprot No.：
  • 別名：
    Srd5a1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
  • 基因功能參考文獻：
    1. Ziram inhibited SRD5A1 and AKR1C14 activities, thus possibly interfering with neurosteroid production in rats. PMID: 28707553
    2. Exposure of middle-aged rats to environmental enrichment increased mRNA levels of 5al;pha-reductase-1, 3alpha-HSD and cytochrome P450 17alpha-hydroxylase/c17,20-lyase and decreased the methylation state of the 5alpha-reductase-1 gene PMID: 26021641
    3. Low Srd5a1 expression is associated with benign prostatic hypertrophy. PMID: 23405234
    4. Changes in the expression of steroid 5-alpha reductase isoenzymes in the prostate in response to environmental stress. PMID: 23122426
    5. Tesosterone concentrations during postnatal sexual differentiation of the rat central nervous system, among other sex-dependent factors, influence brain levels of 5alpha-Reductase isozymes in adulthood PMID: 22131296
    6. Elevated levels of 5alpha-reduced androgens seen in hyperinsulinemic conditions might be explained on the basis of a stimulatory effect of insulin on 5alpha-reductase in granulosa cells. PMID: 20810561
    7. Thus, the present results indicate that the vitamin E-induced regulation of SRD5A1 and GCLM in rat liver is not directly mediated by changes in promoter DNA methylation. PMID: 20447326
    8. 5 alpha-R1 immunostaining was detected mainly in the white matter (Wm). PMID: 15305365
    9. great sexual dimorphism in the central nervous system (CNS) with respect to both 5alpha-reductase isozymes, and suggest a crucial role of dihydrotestosterone in the sexual dimorphism of the CNS in the female PMID: 16595696
    10. Our results demonstrate that both 5alpha-R isozymes are significantly higher in prefrontal cortex of male rats after acute swim stress in comparison with control rats PMID: 17826869
    11. Our results suggest that 5AR inhibitors elicit antipsychotic-like effects in animals and may be proposed as a putative novel target in the management of psychotic disorders. PMID: 18354385

    顯示更多

    收起更多

  • 亞細胞定位：
    Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Steroid 5-alpha reductase family
  • 組織特異性：
    Liver and prostate (at a low level).
  • 數據庫鏈接：


主站蜘蛛池模板： 天干天干夜啦天干天干国产| 欧美一区二区三区久久综合| 蜜臀亚洲精品国产aⅴ综合第一| 高潮毛片无遮挡高清免费视频| 春色校园亚洲愉拍自拍| 精品成人av一区二区三区| 欧美一区内射最近更新| 白嫩无码人妻丰满熟妇啪啪区百度| 永久中文字幕免费视频网站| 日日躁夜夜躁狠狠久久av| 免费无码又爽又刺激高潮视频| 欧美一道本一区二区三区| 欧美日韩无砖专区一中文字| 激情无码人妻又粗又大| 欧美日韩精品一区二区视频| 午夜无码福利伦利理免| 国产精品玩偶在线观看| 欧美成人免费一区二区| 日韩欧美中文字幕在线三区| 少妇爆乳无码专区网站| 熟女肥臀白浆大屁股一区二区| 久久婷婷五月综合色一区二区 | 国产成人综合亚洲色就色| 国产精品aⅴ在线观看| 日韩精品久久久久久免费| 色综合久久无码中文字幕| 国产一二三四区乱码免费| 国产av巨作丝袜秘书| 欧美乱妇高清无乱码| 蜜臀亚洲精品国产aⅴ综合第一| 成人国产一区二区三区精品不卡 | 日韩免费特黄一二三区| 精品成人a区在线观看| 亚洲国产福利一区二区三区 | 亚洲人禽杂交av片久久| 久久丫精品系列| 国产熟睡乱子伦午夜视频| 日韩欧美群交p内射捆绑| 亚洲午夜福利精品无码不卡| 女厕偷窥一区二区三区| 亚洲日本va午夜中文字幕久久|