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  4. Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (Adi1)

Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (Adi1)

  • 中文名稱：
    Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(Adi1)
  • 貨號：
    CSB-YP707068RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(Adi1)
  • 貨號：
    CSB-EP707068RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(Adi1)
  • 貨號：
    CSB-EP707068RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(Adi1)
  • 貨號：
    CSB-BP707068RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(Adi1)
  • 貨號：
    CSB-MP707068RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Adi1
  • Uniprot No.：
  • 別名：
    Adi1; Alp1; Mtcbp1; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; EC 1.13.11.54; Acireductone dioxygenase; Fe(2+)-requiring); ARD; Fe-ARD; Androgen-responsive ARD-like protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MTCBP-1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-179
  • 氨基酸序列
    MVQAWYMDES TADPRMPHRA QPDRPVGLEQ LRTLGVLYWK LDADKYENDP ELEQIRKTRN YSWMDIITIC KDSLPNYEEK IKMFFEEHLH LDEEIRYILE GSGYFDVRDK EDKWIRISME KGDMITLPAG IYHRFTLDEK NYVKAMRLFV GEPVWTPYNR PADHFDARVQ YVKFLEGTA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Induces apoptosis when overexpressed.
  • 基因功能參考文獻：
    1. May have an important role in androgen regulated prostate homeostasis as well as in prostate cancer progression by regulating cell death of prostate cancer cells. PMID: 14684610
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Acireductone dioxygenase (ARD) family
  • 組織特異性：
    Detected in prostate, liver, heart, brain, muscle, kidney and seminal vesicles.
  • 數據庫鏈接：


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