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  4. Recombinant Ras-related protein Rab-3 (rab-3)

Recombinant Ras-related protein Rab-3 (rab-3)

  • 中文名稱：
    秀麗隱桿線蟲rab-3重組蛋白
  • 貨號：
    CSB-YP835998CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲rab-3重組蛋白
  • 貨號：
    CSB-EP835998CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲rab-3重組蛋白
  • 貨號：
    CSB-EP835998CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲rab-3重組蛋白
  • 貨號：
    CSB-BP835998CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲rab-3重組蛋白
  • 貨號：
    CSB-MP835998CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    rab-3
  • Uniprot No.：
  • 別名：
    rab-3; C18A3.6; Ras-related protein Rab-3
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-219
  • 氨基酸序列
    MAAGGQPQGA TPGQPDQNFD YMFKLLIIGN SSVGKTSFLF RYCDDSFTSA FVSTVGIDFK VKTVFRGDKR VKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NSVQDWCTQI KTYSWENAQV VLVGNKCDMD SERVVSMDRG RQLADQLGLE FFETSAKENI NVKAVFEKLV EIICDKMAES LDKDPQQQPK GQKLEANPTQ KPAQQQCNC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord.
  • 基因功能參考文獻：
    1. Our data suggest that AEX-3 activates RAB-3 in the context of AVG axon navigation. PMID: 27116976
    2. Data show that without synaptotagmin 1, the tight coupling between vesicle exocytosis and Rab3 GTP-binding protein membrane disassociation is disrupted. PMID: 25710274
    3. These data suggest a conserved role of RAB-3-/RAB3A-regulated neurotransmitter release in ethanol-related behaviors. PMID: 18397381
    4. Vesicles targeted to the presynaptic density by RAB-3/UNC-10 interactions are ideally positioned for efficient calcium-dependent release. PMID: 18721860
    5. rep-1 does not functions in the RAB-3 pathway, for synaptic transmission at neuromuscular junctions PMID: 19090809

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  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數據庫鏈接：

    STRING: 6239.C18A3.6a

    UniGene: Cel.19709



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