在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1), partial

Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1), partial

  • 中文名稱：
    Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) ,partial
  • 貨號：
    CSB-YP002332RB
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) ,partial
  • 貨號：
    CSB-EP002332RB
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) ,partial
  • 貨號：
    CSB-EP002332RB-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) ,partial
  • 貨號：
    CSB-BP002332RB
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) ,partial
  • 貨號：
    CSB-MP002332RB
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA1; SR Ca(2+)-ATPase 1; EC 7.2.2.10; Calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type; fast twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • 種屬：
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
  • 基因功能參考文獻：
    1. the major SR membrane lipid PC is optimal for all steps and, unlike the other headgroups, contributes favorable electrostatics and non-electrostatic elements during the Ca-ATPase transition PMID: 29032359
    2. ATP-dependent Ca(2+) transport by SERCA in single giant unilamellar vesicles was detected directly using confocal fluorescence microscopy. PMID: 27815070
    3. Glycine 105 as Pivot for a Critical Knee-like Joint between Cytoplasmic and Transmembrane Segments of the Second Transmembrane Helix in Ca2+-ATPase.( PMID: 27733680
    4. Here we describe the methods to analyze these processes in the transport cycle with a representative member of P-type ATPase family, SERCA1a, sarco(endo)plasmic reticulum Ca(2+)-ATPase PMID: 26695035
    5. oligonucleotide-based drugs could be used to fine-tune SERCA function to counterbalance the extent of the pathological insults. PMID: 26292938
    6. Inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA1) by rutin derivatives. PMID: 25467059
    7. Infrared spectroscopy was used to characterise recombinant sarcoplasmic reticulum Ca2+-ATPase (SERCA1a). PMID: 24965041
    8. Data show that biselyngbyasides (BLSs) bind to the pump SERCA1a calcium ATPase near the cytoplasmic surface of the transmembrane region. PMID: 25957767
    9. Cell functions regulated by protein-protein interactions of the SERCA1a-sarcolipin complex is accomplished via s-palmitoylation and s-oleoylation of sarcolipin. PMID: 25301946
    10. Rescue of mutated SERCA1 to sarcoplasmic reticulum membrane can re-establish resting cytosolic Ca(2+) concentration and prevent the appearance of pathological signs of cattle pseudomyotonia PMID: 25288803
    11. Conformation of the SERCA1A calcium ATPase in the presence of different lipids. PMID: 25103814
    12. Ca(2+) and PLB phosphorylation relieve SERCA-PLB inhibition by distinct mechanisms, but both are achieved primarily by structural changes within the SERCA-PLB complex, not by dissociation of that complex. PMID: 24813991
    13. Phosphorylated phospholamban stabilizes a unique conformation of SERCA that is characterized by a compact architecture. PMID: 24138857
    14. Data suggest some phytoestrogenic flavonoids cooperate to inhibit SERCA, alter ATP binding properties of SERCA, and alter phosphorylation/dephosphorylation of SERCA by binding to several sites that are close to ATP binding site. PMID: 24238016
    15. Data suggest that phospholamban PLN's conformational equilibrium is central to maintain sarcoplasmic reticulum Ca(2+)-ATPase SERCA's apparent Ca(2+) affinity within a physiological window. PMID: 24101520
    16. Data suggest that the long-range electrostatics likely guide N and P domain motions in SERCA1a calcium ATPase. PMID: 23737524
    17. Sarcoplasmic reticulum Ca(2+) uptake by SERCA is an integral part of the mechanism by which spontaneous Ca(2+) waves propagate through cardiac myocytes. PMID: 22988145
    18. crystal structure of native SERCA1a (from rabbit) in this E1.Mg(2+) state at 3.0 A resolution in addition to crystal structures of SERCA1a in E2 free from exogenous inhibitors PMID: 23455422
    19. crystal structure of rabbit SERCA1a (also known as ATP2A1) in complex with sarcolipin at 3.1 A resolution PMID: 23455424
    20. CS and SERCA activities were significantly higher in the pubococcygeus (Pc) compared with the ischiocavernosus/bulbospongiosus (Ic/Bs) pelvic floor muscles, whereas the ChAT activity of the Ic/Bs was higher than that of the Pc muscle. PMID: 22911511
    21. On the basis of extended MD simulations with 8 combinations of protonation states of 4 acidic residues in the Ca2+ ion binding sites, data indicate 3 bound protons are sufficient to ensure a stable binding pocket in SERCA. PMID: 22082179
    22. The lipid bilayer composition influences the regulation of SERCA by PLN. PMID: 21992175
    23. Investigations visualize conformational changes in SERCA (in sarcoplasmic reticulum) in real time at single-molecule level. Data suggest catalytic pathway of SERCA is different from the ordinary Albers-Post scheme under physiological conditions. PMID: 21707923
    24. Curcumin could improve cardiac function via upregulating the expression of sarcoplasmic reticulum Ca2+-ATPase. PMID: 20654087
    25. the effects of substitution mutations on the isolated SERCA1a-nucleotide binding domain (SERCA-N) were studied using NMR. PMID: 21187073
    26. Phosphorylation of PLB induces spatial rearrangements between the N- and P-domain elements of proximal Ca-ATPase. PMID: 19191503
    27. Digestion with proteinase K or trypsin yields complementary information on conformational transitions of the Ca(2+)-ATPase (SERCA) in the native membrane environment PMID: 17993458

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIA subfamily
  • 組織特異性：
    Skeletal muscle (at protein level). Skeletal muscle, fast twitch muscle (type II) fibers.
  • 數據庫鏈接：


主站蜘蛛池模板： 少妇被黑人4p到惨叫欧美人| 欧美成人一区二区三区 | av无码久久久久不卡网站下载| 97国产一区二区三区四区久久| 国产精品久久久久久久久久| 婷婷丁香五月中文字幕| 国产精品毛片a∨一区二区三区 | 国产露脸无套对白在线播放| 日韩av无码一区二区三区| 免费午夜无码片在线观看影院| 国产白丝精品爽爽久久蜜臀 | 国产精品美女乱子伦高| 日本高清在线天码一区播放| 最美女人体内射精一区二区| 虎白女粉嫩尤物福利视频| 欧美疯狂做受xxxxx高潮| 亚洲综合色婷婷七月丁香| 中国china体内裑精亚洲日本| 日韩一区二区三区无码人妻视频| a国产一区二区免费入口| 日韩免费无码一区二区视频| 中文字幕人妻熟女av| 国产av无码专区亚洲aⅴ| 精品一区二区三区四区五区六区 | 亚洲乱码在线卡一卡二卡新区豆瓣| 国产在线观看免费人成视频| 漂亮人妻被黑人久久精品| 国产成人一区二区三区影院动漫| 人妻无码中文字幕免费视频蜜桃| 国产亚洲精品久久久久9999 | 可以免费观看的av毛片下载| 小说区 图片区色 综合区| 久久影院午夜理论片无码| 久久人午夜亚洲精品无码区| 亚洲欧美日韩v在线观看不卡| 亚洲国产精品成人无码区| 久久综合伊人九色综合| 亚洲成年看片在线观看| 自拍性旺盛老熟女| 国产内射999视频一区| 国产福利无码一区在线|