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Recombinant Rabbit Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)

  • 中文名稱:
    小圓錐花果DYRK1A重組蛋白
  • 貨號(hào):
    CSB-YP007307RB
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    小圓錐花果DYRK1A重組蛋白
  • 貨號(hào):
    CSB-EP007307RB
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    小圓錐花果DYRK1A重組蛋白
  • 貨號(hào):
    CSB-EP007307RB-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小圓錐花果DYRK1A重組蛋白
  • 貨號(hào):
    CSB-BP007307RB
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小圓錐花果DYRK1A重組蛋白
  • 貨號(hào):
    CSB-MP007307RB
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    DYRK1A; DYRKDual specificity tyrosine-phosphorylation-regulated kinase 1A; EC 2.7.12.1; Dual specificity YAK1-related kinase; Protein kinase minibrain homolog; MNBH; RP86; Fragments
  • 種屬:
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-200
  • 氨基酸序列
    QPSISDQQVS ALPYSDQIQQ PLTNQVMPDI VMLQRRWMDR YEIDSLIGKV EQEWVAIKAF LNQAQIEVRH DTEMKYYIVH LKIVDFGSSC QLGQRIVEVL GIPPAHILDQ APKFFEKLPD GTWSLKKLHN ILGVETGGPG GRFKDLILRM LDYDPKIQPY YALQHSFFKQ ETGIAGHPTY QFSANTGPAH YMTEGHLAMR
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6. Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits TP53 activity and apoptosis.
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily


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