在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Protein lgg-1 (lgg-1)

  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-YP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-EP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-EP600244CXY-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-BP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-MP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    lgg-1
  • Uniprot No.:
  • 別名:
    lgg-1; atg-8.1; C32D5.9Protein lgg-1
  • 種屬:
    Caenorhabditis elegans
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-123
  • 氨基酸序列
    MKWAYKEENN FEKRRAEGDK IRRKYPDRIP VIVEKAPKSK LHDLDKKKYL VPSDLTVGQF YFLIRKRIQL RPEDALFFFV NNVIPQTMTT MGQLYQDHHE EDLFLYIAYS DESVYGGEVE KKE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion during autophagy. Recruits lipidated-lgg-2 to maturing autophagosomes. Acts in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular, binds to components of the unc-51-atg-13 complex to regulate autophagosome formation and cargo sequestration. Required for the degradation of specific sepa-1- and sqst-1-containing protein aggregates during embryogenesis. Involved in allophagy, which is an autophagic process in which paternal mitochondria and organelles are degraded during fertilization, and moreover is required for the formation of lgg-2-positive allophagic autophagosomes in embryos. Involved in the clearance of apoptotic cells by promoting the delivery of engulfed apoptotic cells to the lysosome. Plays a role in the distribution and clearance of germ cell specific P-granules from somatic cells. Also plays a role in the autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes. Involved in xenophagy, the autophagy-mediated degradation of pathogens and pathogen products, such as toxins. Required for normal survival when exposed to pathogenic bacteria S.typhimurium probably by promoting autophagic degradation of intracellular S.typhimurium. Also plays a role in membrane-pore repair. Plays a role in mitophagy. Essential for dauer development and longevity, including longevity in response to moderate, short-term heat shock, also known as a hormetic heat shock.
  • 基因功能參考文獻:
    1. Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins. PMID: 26687600
    2. During allophagy LGG-1 acts upstream of LGG-2 to allow its localization to autophagosomes. PMID: 24374177
    3. both LGG-2 and LGG-1 act synergistically and are involved in dauer formation and longevity of the worm. PMID: 20523114
    4. Inactivation of unc-51, bec-1 and lgg-1, the worm counterparts of the yeast autophagy genes Atg1, Atg6 and Atg8 respectively, partially suppresses degeneration of neurons with toxic ion channel variants. PMID: 17327275
  • 亞細胞定位:
    Preautophagosomal structure. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, autophagosome membrane. Lysosome lumen. Mitochondrion. Cytoplasm. Cytoplasmic vesicle, phagosome membrane. Cell membrane; Lipid-anchor. Cell projection, dendrite. Perikaryon.
  • 蛋白家族:
    ATG8 family
  • 組織特異性:
    Expressed in PLML touch receptor neuron and in the ventral nerve cord. Expressed in AIY interneurons.
  • 數(shù)據(jù)庫鏈接:

    KEGG: cel:CELE_C32D5.9

    STRING: 6239.C32D5.9.1

    UniGene: Cel.23297



主站蜘蛛池模板: 国产成人无码免费视频在线| 午夜dy888国产精品影院| 一本加勒比hezyo无码人妻| 国产天美传媒性色av| 日日噜噜噜夜夜爽爽狠狠视频 | 大地资源中文第3页| 天天看片天天av免费观看| 最近高清中文在线字幕在线观看1 日韩69永久免费视频 | 中文字幕一区二区三区日韩精品 | 精品夜夜澡人妻无码av蜜桃| 精品久久久久国产免费| 久久久久亚洲精品天堂| 亚洲精品国产一二三无码av| 欧美国产日韩a在线视频下载| 天堂在线最新版资源www中文| 午夜免费福利小电影| 秋霞鲁丝无码一区二区三区| 久久露脸国产精品| 中文字幕无码av免费久久| 欧美奶涨边摸边做爰视频| 久久久噜噜噜久久中文字幕色伊伊| 日韩a无v码在线播放| 97精品免费公开在线视频| 精品人妻无码一区二区三区蜜桃一| av无码精品一区二区三区宅噜噜| 一本一道精品欧美中文字幕| 亚洲精品欧美综合四区| 国产成人精品一区二区秒播 | 久久久精品中文字幕乱码18| 屁屁影院ccyy备用地址| 精品无码一区二区三区不卡| 伊人久久久av老熟妇色| 69久久精品无码一区二区无码| 无码熟妇αⅴ人妻又粗又大| 精品人妻少妇一区二区三区不卡| 人妻少妇精品视频无码专区| 午夜高清国产拍精品| 国产成人一区二区三区| yy111111少妇无码理论片| 国产超碰人人做人人爽av| 国产又a又黄又潮娇喘视频 |