在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Protein lgg-1 (lgg-1)

  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-YP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-EP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-EP600244CXY-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-BP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲lgg-1重組蛋白
  • 貨號:
    CSB-MP600244CXY
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    lgg-1
  • Uniprot No.:
  • 別名:
    lgg-1; atg-8.1; C32D5.9Protein lgg-1
  • 種屬:
    Caenorhabditis elegans
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-123
  • 氨基酸序列
    MKWAYKEENN FEKRRAEGDK IRRKYPDRIP VIVEKAPKSK LHDLDKKKYL VPSDLTVGQF YFLIRKRIQL RPEDALFFFV NNVIPQTMTT MGQLYQDHHE EDLFLYIAYS DESVYGGEVE KKE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion during autophagy. Recruits lipidated-lgg-2 to maturing autophagosomes. Acts in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular, binds to components of the unc-51-atg-13 complex to regulate autophagosome formation and cargo sequestration. Required for the degradation of specific sepa-1- and sqst-1-containing protein aggregates during embryogenesis. Involved in allophagy, which is an autophagic process in which paternal mitochondria and organelles are degraded during fertilization, and moreover is required for the formation of lgg-2-positive allophagic autophagosomes in embryos. Involved in the clearance of apoptotic cells by promoting the delivery of engulfed apoptotic cells to the lysosome. Plays a role in the distribution and clearance of germ cell specific P-granules from somatic cells. Also plays a role in the autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes. Involved in xenophagy, the autophagy-mediated degradation of pathogens and pathogen products, such as toxins. Required for normal survival when exposed to pathogenic bacteria S.typhimurium probably by promoting autophagic degradation of intracellular S.typhimurium. Also plays a role in membrane-pore repair. Plays a role in mitophagy. Essential for dauer development and longevity, including longevity in response to moderate, short-term heat shock, also known as a hormetic heat shock.
  • 基因功能參考文獻:
    1. Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins. PMID: 26687600
    2. During allophagy LGG-1 acts upstream of LGG-2 to allow its localization to autophagosomes. PMID: 24374177
    3. both LGG-2 and LGG-1 act synergistically and are involved in dauer formation and longevity of the worm. PMID: 20523114
    4. Inactivation of unc-51, bec-1 and lgg-1, the worm counterparts of the yeast autophagy genes Atg1, Atg6 and Atg8 respectively, partially suppresses degeneration of neurons with toxic ion channel variants. PMID: 17327275
  • 亞細胞定位:
    Preautophagosomal structure. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, autophagosome membrane. Lysosome lumen. Mitochondrion. Cytoplasm. Cytoplasmic vesicle, phagosome membrane. Cell membrane; Lipid-anchor. Cell projection, dendrite. Perikaryon.
  • 蛋白家族:
    ATG8 family
  • 組織特異性:
    Expressed in PLML touch receptor neuron and in the ventral nerve cord. Expressed in AIY interneurons.
  • 數(shù)據(jù)庫鏈接:

    KEGG: cel:CELE_C32D5.9

    STRING: 6239.C32D5.9.1

    UniGene: Cel.23297



主站蜘蛛池模板: 人人玩人人添人人澡欧美| 真人啪啪高潮喷水呻吟无遮挡| 中文无码伦av中文字幕在线| 欧美性生交xxxxx无码久久久 | 无码人妻精品一区二区三区蜜桃| 国产一区二区三区美女| 亚洲日韩成人无码| 女人被狂躁c到高潮| 99精品视频在线观看婷婷| 亚洲精品av一二三区无码| 久久午夜夜伦鲁鲁片免费无码影视| 深夜国产一区二区三区在线看| 无码日韩精品一区二区三区免费| 欧美最新精品videossexohd| 性色av免费网站| 亚洲精品乱码久久久久久不卡| 四虎国产精品永久入口| 国产高清-国产av| 国产av无码精品色午夜| 亚洲熟女少妇一区二区| 免费纯肉3d动漫无码网站| 一出一进一爽一粗一大视频免费的| 久久99亚洲含羞草影院| 在教室伦流澡到高潮h麻豆| 无码精品国产va在线观看| 日日摸夜夜添夜夜添无码| 亚无码乱人伦一区二区| 久久无码中文字幕无码| 亚洲精品午夜一区二区电影院| 青青草视频免费观看| 无码国产69精品久久久久孕妇| 香蕉人妻av久久久久天天| 岛国4k人妻一区二区三区| 国产又黄又湿无遮挡免费视频| 中文无码日韩欧| 99久久久国产精品免费蜜臀| 久久99精品久久久久婷婷暖| 精品国内自产拍在线观看| 久久中文骚妇内射| 久久国产成人午夜av影院| 激情综合激情五月俺也去|