在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Protein E6 (E6)

  • 中文名稱(chēng):
    Recombinant Protein E6(E6)
  • 貨號(hào):
    CSB-YP346194HOK
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    Recombinant Protein E6(E6)
  • 貨號(hào):
    CSB-EP346194HOK
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    Recombinant Protein E6(E6)
  • 貨號(hào):
    CSB-EP346194HOK-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    Recombinant Protein E6(E6)
  • 貨號(hào):
    CSB-BP346194HOK
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    Recombinant Protein E6(E6)
  • 貨號(hào):
    CSB-MP346194HOK
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    E6; Protein E6
  • 種屬:
    Human papillomavirus type 68
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-158
  • 氨基酸序列
    MALFHNPEER PYKLPDLCRT LDTTLHDVTI DCVYCRRQLQ RTEVYEFAFS DLCVVYRDGV PFAACQSCIK FYAKIRELRY YSESVYATTL ETITNTKLYN LLIRCMSCLK PLCPAEKLRH LTTKRRLHKI AGNFTGQCRH CWTSKREDRR RIRQETQV
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細(xì)胞定位:
    Host cytoplasm. Host nucleus.
  • 蛋白家族:
    Papillomaviridae E6 protein family


主站蜘蛛池模板: 少妇的丰满3中文字幕| 一本大道东京热无码aⅴ| 久久久无码精品亚洲日韩蜜桃| 亚洲欧美日韩成人综合一区| 精品国内自产拍在线观看| 亚洲bbw性色大片| 白天躁晚上躁麻豆视频| 日本无遮挡真人祼交视频| 国产一卡2卡3卡四卡精品国色无边 | 成人看片黄a免费看在线| 人人爽久久久噜人人看| 国产微拍精品一区二区| 怡红院av亚洲一区二区三区h| 国产精品av免费观看| 在线观看国产成人av片| 日本成熟少妇喷浆视频| 老司机在线精品视频播放| 人人妻人人澡人人爽人人精品浪潮| 亚洲成a人片77777国产| 把腿张开老子臊烂你多p视频 | 精品国产美女av久久久久| 尹人香蕉99久久综合网站| 亚洲人成网站色7799| 麻豆av一区二区三区久久| 97人妻免费公开在线视频| 麻豆国产成人av高清在线| 狠狠色噜噜狠狠狠8888米奇| 日本在线看片免费人成视频| 成人亚洲精品777777| www国产无套内射com| 国产精品18久久久| 国产精品高潮露脸在线观看| 欧美最新精品videossexohd| 内射无码专区久久亚洲| 在线综合亚洲欧美网站| 无码一区二区免费波多野播放搜索| 丰满少妇被猛烈进入无码| 精品无码日韩一区二区三区不卡 | 可以免费观看的av毛片下载| 国产精品久久久久久一区二区三区| 久久亚洲中文字幕伊人久久大|