在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Protein E6 (E6)

Recombinant Protein E6 (E6)

  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-YP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-EP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-EP335272HNH-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-BP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-MP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    E6; Protein E6
  • 種屬：
    Human papillomavirus type 35
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-149
  • 氨基酸序列
    MFQDPAERPY KLHDLCNEVE ESIHEICLNC VYCKQELQRS EVYDFACYDL CIVYREGQPY GVCMKCLKFY SKISEYRWYR YSVYGETLEK QCNKQLCHLL IRCITCQKPL CPVEKQRHLE EKKRFHNIGG RWTGRCMSCW KPTRRETEV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    This protein may be involved in the oncogenic potential of this virus (associated with cancer of the uterine cervix).; Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細胞定位：
    Host cytoplasm. Host nucleus.
  • 蛋白家族：
    Papillomaviridae E6 protein family


主站蜘蛛池模板： 波多野结衣爽到高潮大喷| 男人j桶进女人p无遮挡免费观看 | 亚洲国产精品成人天堂| 日本一区二区三区免费视频 | 四虎www永久在线精品| 久久青青草原精品国产| 亚洲自偷精品视频自拍| 国产精品久久久久久一区二区三区| 欧美亚洲日韩国产网站| 无码av片在线观看免费| 妺妺窝人体色www在线观看| 韩日午夜在线资源一区二区| 人妻丰满熟妇av无码区hd| 亚洲欧洲自拍拍偷精品 美利坚| 日本19禁啪啪吃奶大尺度| 99精品国产福久久久久久| 亚洲中文无码永久免费| 成人欧美一区二区三区在线| 岛国4k人妻一区二区三区| 国产精品无码翘臀在线看| 人与性动交aaaabbbb| 美女高潮黄又色高清视频免费| 曰本极品少妇videossexhd| 99久久精品费精品国产一区二| 东京热无码av男人的天堂| 亚洲性无码av在线欣赏网| 人人狠狠综合久久88成人 | 欧美黑人疯狂性受xxxxx喷水| 免费午夜无码片在线观看影院| 国产片免费福利片永久| 成人女人看片免费视频放人| 中年熟妇的大黑p| 日韩精品无码一本二本三本| 最近中文字幕mv在线视频看 | 久久精品高清一区二区三区| 米奇7777狠狠狠狠视频影院 | 人妻av无码一区二区三区| 久久久无码中文字幕久...| 人妻中文字幕无码系列| 99久久伊人精品综合观看| 国产成人拍精品视频午夜网站|