在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Protein E6 (E6)

Recombinant Protein E6 (E6)

  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-YP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-EP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-EP335272HNH-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-BP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Protein E6(E6)
  • 貨號：
    CSB-MP335272HNH
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    E6; Protein E6
  • 種屬：
    Human papillomavirus type 35
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-149
  • 氨基酸序列
    MFQDPAERPY KLHDLCNEVE ESIHEICLNC VYCKQELQRS EVYDFACYDL CIVYREGQPY GVCMKCLKFY SKISEYRWYR YSVYGETLEK QCNKQLCHLL IRCITCQKPL CPVEKQRHLE EKKRFHNIGG RWTGRCMSCW KPTRRETEV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    This protein may be involved in the oncogenic potential of this virus (associated with cancer of the uterine cervix).; Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細胞定位：
    Host cytoplasm. Host nucleus.
  • 蛋白家族：
    Papillomaviridae E6 protein family


主站蜘蛛池模板： 国产乱人伦av麻豆网| 亚洲曰本av在线天堂| 亚洲大码熟女在线观看| 男女一边摸一边做爽爽的免费阅读| 精品偷拍一区二区三区在线看| 国产午夜精品一区二区| 欧洲性久久精品| 影音先锋无码a∨男人资源站 | 日本嫩交12一16xxx视频| 粗大的内捧猛烈进出在线视频| 无码专区aaaaaa免费视频| 天堂官网在线资源网| 无码av不卡免费播放| 夜夜夜夜猛噜噜噜噜噜| 国产又黄又猛又粗又爽的a片动漫| 国产精品无码av无码| 国产成人亚洲综合网站小说| 亚洲自偷自拍另类11p| 国产精品久久久久9999| 欧美性生交大片免费看| 精品国产av最大网站| 国产产品亚洲产品| 胸大美女又黄的网站| 人妻精品久久久久中文字幕| 国产系列丝袜熟女精品网站| 狠狠躁天天躁中文字幕无码| 少妇脱了内裤让我添| 亚洲人成网站在线播放影院在线 | 女女互磨互喷水高潮les呻吟| 亚洲精品熟女国产| 四十如虎的丰满熟妇啪啪| 国产在热线精品视频| 精久国产av一区二区三区孕妇| 亚洲 综合 校园 欧美 制服 | 人妻熟女一区二区aⅴ水野朝阳| 国产又色又爽又黄的免费| 麻豆亚洲一区| 波多野结衣中文字幕久久| 国产精品毛片在线完整版| 精品国产va久久久久久久冰| 午夜无码片在线观看影院|