Recombinant Probable ubiquitin carboxyl-terminal hydrolase 46 (usp-46)

中文名稱：

秀麗隱桿線蟲usp-46重組蛋白
貨號：

CSB-YP341545CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲usp-46重組蛋白
貨號：

CSB-EP341545CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲usp-46重組蛋白
貨號：

CSB-EP341545CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲usp-46重組蛋白
貨號：

CSB-BP341545CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲usp-46重組蛋白
貨號：

CSB-MP341545CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

usp-46
Uniprot No.：

P34547
別名：

usp-46; R10E11.3Ubiquitin carboxyl-terminal hydrolase 46; EC 3.4.19.12; Deubiquitinating enzyme; Ubiquitin thioesterase; Ubiquitin-specific-processing protease
種屬：

Caenorhabditis elegans
蛋白長度：

Full Length of Mature Protein
表達區域：

2-426
氨基酸序列

GATGSSQLE KEISTTESVN NANEHYYGLV NFGNTCYCNS VIQALFFCRP FREKVLNYKQ TLKKSGASKD NLVTCLADLF HSIASQKRRV GTIAPKRFIT KLKKENELFD NYMQQDAHEF FNYLINTISE TLIQEKIAER EKASRHGTLK KGNVTVNLAP ATAGLPRSDE KGTSERNGGI TVEGNEFLNK SDTTTWIHEI FQGILTNETR CLSCETVSSK DEDFLDLSID VEQNTSISHC LRVFSETETL CGDQKYFCET CSSKQEAQKR MRIKKPPQLL ALHLKRFKFV EPLNRHTKLS YRVVFPLELR LFNVSDDAEY GDRMYDLVAT VVHCGATPNR GHYITLVKSN SFWLVFDDDI VEKLEVSSME EFSGMSTDAN IQMPPGNQSA PQKNSESAYI LFYQARDYAA DDPNHNHKGK NSTHSV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Regulates the abundance of the glr-1 glutamate receptor in the ventral nerve cord by promoting its deubiquitination and preventing its degradation in the lysosome. Contributes to the regulation of embryonic polarity.
基因功能參考文獻：
1. The deubiquitinating enzyme ubiquitin-specific protease-46 (USP-46) regulates the abundance of the glutamate receptor GLR-1 in the ventral nerve cord of Caenorhabditis elegans. PMID: 21273419
亞細胞定位：

Perikaryon. Cytoplasm. Note=In ventral nerve cord interneurons, localized to discrete puncta within the perikaryon. In the ventral nerve cord, localized diffusely throughout the cytoplasm and to punctate structures.
蛋白家族：

Peptidase C19 family
組織特異性：

Expressed in a number of tissues including the nervous system, pharynx, body wall muscle, vulva muscle and intestine and is detected in many head and ventral cord neurons.
數據庫鏈接：

KEGG: cel:CELE_R10E11.3

STRING: 6239.R10E11.3a.2

UniGene: Cel.6955