在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pongo abelii Heat shock 70 kDa protein 1 (HSPA1), partial

  • 中文名稱:
    波戈阿貝利HSPA1重組蛋白
  • 貨號:
    CSB-YP716079PYX
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    波戈阿貝利HSPA1重組蛋白
  • 貨號:
    CSB-EP716079PYX
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    波戈阿貝利HSPA1重組蛋白
  • 貨號:
    CSB-EP716079PYX-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    波戈阿貝利HSPA1重組蛋白
  • 貨號:
    CSB-BP716079PYX
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    波戈阿貝利HSPA1重組蛋白
  • 貨號:
    CSB-MP716079PYX
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    HSPA1
  • Uniprot No.:
  • 別名:
    HSPA1; Heat shock 70 kDa protein 1
  • 種屬:
    Pongo abelii (Sumatran orangutan)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The co-chaperones are of three types: J-domain co-chaperones such as HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Maintains protein homeostasis during cellular stress through two opposing mechanisms: protein refolding and degradation. Its acetylation/deacetylation state determines whether it functions in protein refolding or protein degradation by controlling the competitive binding of co-chaperones HOPX and STUB1. During the early stress response, the acetylated form binds to HOPX which assists in chaperone-mediated protein refolding, thereafter, it is deacetylated and binds to ubiquitin ligase STUB1 that promotes ubiquitin-mediated protein degradation. Regulates centrosome integrity during mitosis, and is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle. Enhances STUB1-mediated SMAD3 ubiquitination and degradation and facilitates STUB1-mediated inhibition of TGF-beta signaling. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation.
  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族:
    Heat shock protein 70 family
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲人成77在线播放网站| 天堂а√在线地址8中文种子| 内射小寡妇无码| 亚洲色爱免费观看视频| 国产精品va在线观看丝瓜影院| 中国大陆精品视频xxxx| 亚洲 欧美 综合 另类 中字| 国产精品久线在线观看| 国产无遮挡又黄又爽又色| 免费国产va在线观看| 日本无码人妻精品一区二区蜜桃| 国产午夜亚洲精品理论片不卡| 最新在线精品国自产拍视频| 亚洲日韩一区二区| 午夜精品一区二区三区免费视频| 国产午夜伦鲁鲁| 亚洲中文字幕码在线电影| 中文人妻av大区中文不卡| 太粗太深了太紧太爽了动态图男男| 日本一区二区三区免费高清| 亚洲一区精品二人人爽久久| 国产xxxx做受性欧美88| 免费永久看黄神器无码软件| 伊人中文字幕无码专区| 国产精品99久久久久久人| 精品人妻少妇一区二区三区不卡| 未满十八勿入av网免费| 男人扒开女人双腿猛进免费视频| 熟妇五十路六十路息与子| 人妻少妇中文字幕久久| 日日鲁鲁鲁夜夜爽爽狠狠 | 亚洲日韩高清在线亚洲专区| 久热这里只有精品99| 大伊香蕉精品视频在线直播| 野花社区视频www官网| 久久久久人妻精品一区蜜桃| 人妻少妇精品视频无码综合| 久久无码精品一一区二区三区| 好爽好黄的视频| 三级视频兔费看| 2020最新无码福利视频|