在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Pig Signal transducer and activator of transcription 1 (STAT1), partial

Recombinant Pig Signal transducer and activator of transcription 1 (STAT1), partial

  • 中文名稱：
    野豬STAT1重組蛋白
  • 貨號：
    CSB-YP741715PI
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬STAT1重組蛋白
  • 貨號：
    CSB-EP741715PI
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬STAT1重組蛋白
  • 貨號：
    CSB-EP741715PI-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬STAT1重組蛋白
  • 貨號：
    CSB-BP741715PI
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬STAT1重組蛋白
  • 貨號：
    CSB-MP741715PI
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    STAT1; Signal transducer and activator of transcription 1
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
  • 基因功能參考文獻：
    1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon response by inducing STAT1 degradation. PMID: 27384656
    2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets PMID: 27160867
    3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK-STAT1) signaling pathway. PMID: 25357264
    4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 nuclear translocation. PMID: 24554650
    5. Nsp1beta inhibits interferon-activated STAT1/STAT2 signal transduction by inducing karyopherin-alpha1 degradation. PMID: 23449802
    6. STAT1 is involved in mediating the action of ghrelin on ovarian cell functions. PMID: 19528263
    7. the majority of the STAT1/STAT2/IRF9 (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked PMID: 20739522
    8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation. PMID: 17525118
    9. Nitric oxide-dependent increase in caspase-8 mRNA levels is associated with phosphorylation of STAT-1 at Ser-727 and STAT1 binding to the caspase-8 promoter in cultured lung endothelial cells. PMID: 17565448
    10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation. PMID: 18774104
    11. The tight junction protein ZO-2 is involved in regulation of vascular smooth muscle cells growth control upon vascular injury that is mediated by the transcription factor Stat1. PMID: 19380416

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Transcription factor STAT family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲gv天堂无码男同在线观看| 99草草国产熟女视频在线| 天堂资源中文网| 无码av免费一区二区三区a片| 亚洲不卡1卡2卡三卡入口| 亚洲午夜成人av电影| 欧美老熟妇乱大交xxxxx| 天天天天做夜夜夜夜做无码| 亚洲中文无码永久免| 蜜臀国产在线视频| 国产精品人人爽人人做我的可爱| 国产精品亚洲精品日韩己满十八小| 国内精品久久久久久久影视麻豆| 欧洲女人牲交视频免费| 久久久久无码精品国产不卡| 中文国产乱码在线人妻一区二区| 中文字幕av无码免费一区| 久久久久久久久久久久久9999| 人妻熟女一区二区aⅴ向井蓝| 亚洲综合日韩久久成人av| 欧洲一卡2卡3卡4卡乱码视频| 成人h动漫精品一区二区无码| 波多野结衣中文字幕久久| 日本丰满岳乱妇在线观看| 国产欧美日韩中文久久| 国产不卡视频一区二区三区| 玩弄放荡人妇系列av在线网站| 国产乱子伦一区二区三区四区五区| 青青草视频在线观看| 99精品国产在热久久无码| 无码少妇一区二区三区免费| 精品免费国产一区二区三区四区介绍 | 成人免费乱码大片a毛片| 日本一区二区在线播放| 网友自拍区视频精品| 国产免费福利在线视频| 日本少妇被黑人猛cao| 久久精品久久电影免费理论片 | 国产精品成人无码久久久| 99久久国产亚洲高清观看| 五月婷婷久久草丁香|