在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Pleiotrophin (PTN)

  • 中文名稱:
    野豬PTN重組蛋白
  • 貨號:
    CSB-YP019009PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    野豬PTN重組蛋白
  • 貨號:
    CSB-EP019009PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    野豬PTN重組蛋白
  • 貨號:
    CSB-EP019009PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    野豬PTN重組蛋白
  • 貨號:
    CSB-BP019009PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    野豬PTN重組蛋白
  • 貨號:
    CSB-MP019009PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PTN
  • Uniprot No.:
  • 別名:
    PTN; Pleiotrophin; PTN; Pleiotrophic factor beta; PTF-beta
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    33-168
  • 氨基酸序列
    GKKEKPEK KVKKSDCGEW QWSVCVPTSG DCGLGTREGT RTGAECKQTM KTQRCKIPCN WKKQFGAECK YQFQAWGECD LNTALKTRTG SLKRALHNAD CQKTVTISKP CGKVTKPKPQ AESKKKKKEG KKQEKMLD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Secreted growth factor that mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups. Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone. Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation. Binds PTPRZ1, leading to neutralization of the negative charges of the CS chains of PTPRZ1, inducing PTPRZ1 clustering, thereby causing the dimerization and inactivation of its phosphatase activity leading to increased tyrosine phosphorylation of each of the PTPRZ1 substrates like ALK, CTNNB1 or AFAP1L2 in order to activate the PI3K-AKT pathway. Through PTPRZ1 binding controls oligodendrocyte precursor cell differentiation by enhancing the phosphorylation of AFAP1L2 in order to activate the PI3K-AKT pathway. Forms a complex with PTPRZ1 and integrin alpha-V/beta-3 (ITGAV:ITGB3) that stimulates endothelial cell migration through SRC dephosphorylation and activation that consequently leads to ITGB3 'Tyr-773' phosphorylation. In adult hippocampus promotes dendritic arborization, spine development, and functional integration and connectivity of newborn granule neurons through ALK by activating AKT signaling pathway. Binds GPC2 and chondroitin sulfate proteoglycans (CSPGs) at the neuron surface, leading to abrogation of binding between PTPRS and CSPGs and neurite outgrowth promotion. Binds SDC3 and mediates bone formation by recruiting and attaching osteoblasts/osteoblast precursors to the sites for new bone deposition. Binds ALK and promotes cell survival and cell proliferation through MAPK pathway activation. Inhibits proliferation and enhances differentiation of neural stem cells by inhibiting FGF2-induced fibroblast growth factor receptor signaling pathway. Mediates regulatory mechanisms in normal hemostasis and in hematopoietic regeneration and in maintaining the balance of myeloid and lymphoid regeneration. In addition may play a role in the female reproductive system, auditory response and the progesterone-induced decidualization pathway.
  • 基因功能參考文獻:
    1. a heparin-binding growth factor, produced mainly by glia cells, was the predominant binding partner for chondroitin and dermatan sulfate hybrid chain biosynthesis. PMID: 15632143
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Pleiotrophin family
  • 數據庫鏈接:


主站蜘蛛池模板: 综合偷自拍亚洲乱中文字幕| 国产精品性夜天天拍拍2021| 久久亚洲国产最新网站之一| 免费看小12萝裸体视频国产| 欧美精品国产综合久久| 欧美黑人添添高潮a片www| 99j久久精品久久久久久| 欧美成人精品 一区二区三区| 久久国产乱子伦精品免费台湾| 国产色视频一区二区三区qq号| 成人网站免费观看| 凸偷窥中国女人洗澡| 精品亚洲国产成人av不卡| 国产精品亚韩精品无码a在线| 国产成人综合色在线观看网站| 国产成人无码免费视频麻豆| 国产精品玖玖玖在线| 三个男吃我奶头一边一个视频| 人妻教师痴汉电车波多野结衣 | 国产一区二区野外| 成 人 社区在线视频| 在线观看国产精品普通话对白精品| 欧美性xxxxx极品娇小| 国产亚洲欧美另类一区二区| 欧美特级婬片毛多的少妇| 亚洲精品卡2卡三卡4卡2卡乱码| 野花社区www视频最新资源| 九九九国产精品成人免费视频| 18禁裸乳无遮挡啪啪无码免费 | 精品免费国产一区二区三区四区| 男女性杂交内射妇女bbwxz| 狠狠久久久久综合成人影院| 亚洲人成无码网站在线观看| 精品国产aⅴ无码一区二区 | 2020最新国产高清毛片| 影音先锋啪啪av资源网站| 亚洲国产中文在线二区三区免| 在线观看国产成人av天堂| 亚洲手机在线人成网站| 国产成人无码一区二区三区| 久久久欧美国产精品人妻噜噜|